Cones release glutamate-filled vesicles continuously in darkness, and changing illumination modulates this release. Because sustained release in darkness is governed by vesicle replenishment rates, we analyzed how cone membrane potential regulates replenishment. Synaptic release from cones was measured by recording postsynaptic currents in Ambystoma tigrinum horizontal or OFF bipolar cells evok...

Supply contracts are designed to minimize inventory costs or to hedge against undesirable events (e.g., shortages) in the face of demand or supply uncertainty. In particular, replenishment terms stipulated by supply contracts need to be optimized with respect to overall costs, profits, service levels, etc. In this paper, we shall be primarily interested in minimizing an inventory cost function ...

This paper presents an inventory model for deteriorating items over a ®nite time horizon where the demand increases linearly with time. The method is developed by assuming that the successive replenishment cycle lengths are the same. Many O.R. scientists/researchers obtained an optimal replenishment schedule where the replenishment cost is constant in each cycle length over the ®nite time horiz...

Abstract Interaction effect across complementary products plays an important role in characterizing the optimal inventory policy. The levels of are interrelated due to interaction between demand streams. In this paper, we consider a periodic review base-stock policy presence two with demands and joint replenishment. Demands modeled by Poisson process any unmet is lost. can be sets one unit each...

This paper examines several inventory replenishment policies for a make-to-order inventory–production system that consists of a production workshop and a warehouse. Demands arrive to the production workshop according to a Poisson process, and are processed in an FCFS manner. The production workshop requires that the warehouse provides, as needed, raw materials for use in the production process....

This paper deals with an optimal replenishment policy for deteriorating items with multi-variate demand and partial backlogging. The proposed model allows for (1) multivariate demand replenishment cycles, (2) partial backlogging, and (3) time-varying shortage intervals. Consequently, the proposed model is in a general framework for that inventory models includes these above assumptions. We show...