OBJECTIVE Postoperative nausea and vomiting are distressing and frequent adverse events of anesthesia and surgery, with a high incidence following thyroidectomy. The aim of this study was to evaluate the efficacy of low-dose midazolam for preventing postoperative nausea and vomiting in patients undergoing thyroidectomy. STUDY DESIGN Prospective, randomized, double-blind, placebo-controlled st...

Objective: To assess the efficacy of ondansetron and dexamethasone in the prevention of nausea and vomiting in patients undergoing laparoscopic cholecystectomy. Material and Methods: This study was conducted at the Department of Surgery, Khyber Teaching Hospital, Peshawar from May 2010 to December 2010. A total of 67 patients, aged 18 years and above, scheduled for elective cholecystectomy were...

Postoperative nausea and vomiting continues to occur in approximately one-third of patients who have surgery despite newer medications and emerging guidelines for care. There is a paucity of literature that relates to patients who experience postdischarge nausea and vomiting after outpatient surgery. The purpose of this article is to review the current knowledge in the area of postdischarge nau...

BACKGROUND Postoperative pruritus, nausea, and vomiting are common side effects of intrathecal or epidural opioids. Intravenous ondansetron has been used for postoperative emesis. However, there are no reports regarding epidural ondansetron. Two studies were conducted to evaluate the prophylactic effects of epidural ondansetron for opioid-induced pruritus, nausea, and vomiting. METHODS Neurot...

BACKGROUND We investigated the effects of a novel method of anesthesia combining propofol and volatile anesthesia on the incidence of postoperative nausea and vomiting in patients undergoing laparoscopic gynecological surgery. METHODS Patients were randomly divided into three groups: those maintained with sevoflurane (Group S, n=42), propofol (Group P, n=42), or combined propofol and sevoflur...

background the involved neurotransmitter pathways in the postoperative shivering (pos) are poorly understood. recently, 5-hydroxytryptamine 3 (5-ht3) receptor antagonists have been reported to prevent pos. we investigated the effect of ondansetron, a 5-ht3 antagonist that is used to treat postoperative nausea and vomiting, on shivering. objectives this study aimed to compare the efficacy of ond...

BACKGROUND Iletrospective studies fail to identify predictors of postoperative nausea and vomiting (PONV). The authors prospectively studied 17,638 consecutive outpatients who had surgery to identify predictors. METHODS Data on medical conditions, anesthesia, surgery, and PONV were collected in the post-anesthesia care unit, in the ambulatory surgical unit, and in telephone interviews conduct...

Knowledge of postoperative nausea and vomiting (PONV) risk factors allows anesthesiologists to optimize the use of prophylactic regimens. Modern PONV risk research began in the 1990s with publication of studies using logistic regression analysis to simultaneously identify multiple independent PONV predictors and publication of meta-analyses and systematic reviews. This literature shows that fem...

Forty-two patients, undergoing major gynaecological surgery, were randomly allocated to have a patch applied to the skin behind one ear, containing either hyoscine or placebo. They were followed up at 24-hour intervals for 3 days postoperatively and divided into matched pairs for statistical analysis. There was a significant (p less than 0.01) reduction in nausea and vomiting in the first 24 ho...