Anogenital cancers, in particular cancer of the cervix, and common, genital and laryngeal warts are primarily caused by infection with human papillomaviruses. Traditionally, the primary goal of treatment is to remove the neoplasia by various surgical approaches; however, all of these have high rates of recurrence. Only a few non-surgical treatments have found their way into clinical practice, a...

Multipotent mesenchymal stromal cells or mesenchymal stem cells (MSCs) are mainly isolated from bone marrow or fat tissue. Because of their potential of multilineage differentiation towards bone, cartilage and fat tissue, they were initially evaluated to develop innovative strategies for tissue engineering applications. More recently, they have gained interest based on their immunomodulatory pr...

Due to the economic and social priorities afforded health services in the United States, research on new delivery modalities such as the Internet is gaining in popularity. Claims of the Internet's potential range from a promise to revolutionize the fundamental way health care is delivered to a tool for empowering patients through enhanced interaction with providers (Rice, 2001). Even though a g...

In this paper, rstly, potential synthesis cases in distributed expert systems (DESs) and types of DESs are identiied. Based on these results, necessary conditions of synthesis strategies in diierent synthesis cases are recognized. Secondly, two methodologies for designing synthesis strategies in distributed expert systems are investigated. They are analysis methods, and inductive methods. Third...

This article offers some remarks on a few critical issues related to explanation in criminal network research. It first discusses two distinct perspectives on networks, namely a substantive approach that views networks as a distinct form of organisation, and an instrumental one that interprets networks as a collection of nodes and attributes. The latter stands at the basis of Social Network Ana...

We investigated the spatial genetic structure of the tiger meta-population in the Satpura-Maikal landscape of central India using population- and individual-based genetic clustering methods on multilocus genotypic data from 273 individuals. The Satpura-Maikal landscape is classified as a global-priority Tiger Conservation Landscape (TCL) due to its potential for providing sufficient habitat tha...

Density dependence, population regulation, and variability in population size are fundamental population processes, the manifestation and interrelationships of which are affected by environmental variability. However, there are surprisingly few empirical studies that distinguish the effect of environmental variability from the effects of population processes. We took advantage of a unique syste...

The web has changed the way we do things in a variety of ways. It is not uncommon to associate the term disruptive technologies to the radical changes happening on the web. This paper takes an encompassing view of developments surrounding the web with a particular emphasis on emerging trends and evolving application scenarios. We provide a broad overview of technologies, in revealing directions...

Although GQM+Strategies® 1 assures that business goals and strategies are aligned throughout an organization and at each organizational unit based on the rationales to achieve the overall business goals, whether the GQM+Strategies grid is created correctly cannot be determined because the current definition of GQM+Strategies allows multiple perspectives when aligning goals with strategies. Here...

Most of today’s products and services are software-based. Organizations that develop software want to maintain and improve their competitiveness by controlling software-related risks. To do this, they need to align their business goals with software development strategies and translate them into quantitative project management. There is also an increasing need to justify cost and resources for ...