The sucrose non-fermenting 1-related protein kinase 2 (SnRK2) family members are plant unique serine/threonine kinases which play a key role in cellular signaling in response to abiotic stresses. The three SnRK2 members including SRK2D, SRK2I and SRK2E are known to phosphorylate major abscisic acid (ABA) responsive transcription factors, ABF2 and ABF4, involved in an ABA-dependent stress signal...

Pattern mining is an essential part of knowledge discovery and data analytics. It a powerful paradigm, especially when combined with constraint reasoning. In this paper, we present Seq2Pat, constraint-based sequential pattern tool high-level declarative user interface. The library finds patterns that frequently occur in large sequence databases subject to constraints. We highlight key benefits ...

osmotic stress is one of the major factors that significantly reduce yields in dry areas. plants respond to this abiotic stress at physiological and molecular levels. many genes are induced under stress conditions by transcription factors. dehydration responsive element binding (dreb) protein is a subfamily of ap2/erf transcription factors which control expression of many osmotic stress-inducib...

In an era that has been dominated by Structural Biology for the last 30-40 years, a dramatic change of focus towards sequence analysis has spurred the advent of the genome projects and the resultant diverging sequence/structure deficit. The central challenge of Computational Structural Biology is therefore to rationalize the mass of sequence information into biochemical and biophysical knowledg...

Diversity among the pathogenic strains of Theileria equi (T. equi), a major agent of equine piroplasmosis, can affect the appropriate detection of parasite and host immunization. Production of recombinant surface proteins from an infected horse in natural endemic area provides a reliable tool for immunodiagnosis of parasite. Regarding this, the present study was targeted toward the cloning, exp...

Pattern matches for each of the sequence patterns in PROSITE, a database of sequence patterns, were searched in all protein sequences in the Brookhaven Protein Data Bank (PDB). The three-dimensional structures of the pattern matches for the 20 patterns with the largest numbers of hits were analysed. We found that the true positives have a common three-dimensional structure for each pattern; the...

Members of the Coronaviridae family comprise four genera Alphacoronavirus and Betacoronavirus, which infect only mammals, Gammacoronavirus Deltacoronavirus birds mammals. Since end 2019, humanity has witnessed emergence a new pandemic caused by line beta-coronavirus (SARS-CoV-2) responsible for causing novel severe acute respiratory syndrome named coronavirus disease (COVID-19) affecting countr...