نتایج جستجو برای: proteomics techniques

تعداد نتایج: 656517  

Journal: :Current opinion in biotechnology 2015
Andrew Landels Caroline Evans Josselin Noirel Phillip C Wright

Proteomics is the large-scale study and analysis of proteins, directed to analysing protein function in a cellular context. Since the vast majority of the processes occurring in a living cell rely on protein activity, proteomics offer a unique vantage point from which researchers can dissect, characterise, understand and manipulate biological systems. When developing a production strain, proteo...

2004
Weichuan Yu Baolin Wu Tao Huang Xiaoye Li Kenneth Williams Hongyu Zhao

Proteomics technologies are rapidly evolving and attracting great attention in the post-genome era. In this chapter, we review two key applications of proteomics techniques: disease biomarker discovery and protein/peptide identification. For each of the applications, we will state the major issues related to statistical modeling and analysis, review related work, discuss their strength and weak...

Journal: :Journal of proteomics 2014
Thierry Rabilloud

UNLABELLED Taking the opportunity of the 20th anniversary of the word "proteomics", this young adult age is a good time to remember how proteomics came from enormous progress in protein separation and protein microanalysis techniques, and from the conjugation of these advances into a high performance and streamlined working setup. However, in the history of the almost three decades that encompa...

2015
Fotis E. Psomopoulos Pericles A. Mitkas

The scope of this chapter is the presentation of Data Mining techniques for knowledge extraction in proteomics, taking into account both the particular features of most proteomics issues (such as data retrieval and system complexity), and the opportunities and constraints found in a Grid environment. The chapter discusses the way new and potentially useful knowledge can be extracted from proteo...

پایان نامه :وزارت علوم، تحقیقات و فناوری - دانشگاه زنجان - دانشکده علوم انسانی و اجتماعی 1392

most specialists in the field of foreign language teachingconsiderreading skill as an interactive process between the reader’s prior knowledge and the text.accordingly, the activation of prior knowledge for an effective comprehension is very important. it is generally agreed that the pre-reading phase is the stage where this type of interaction and activation may be enhanced throughcertain stra...

Journal: :iranian journal of biotechnology 2008
seyed abbas shojaosadati seyedeh marjan varedi kolaei valiollah babaeipour amir mohammad farnoud

this paper reviews recent strategies used for increasing specific yield and productivity in high cell density cultures. high cell density cultures offer an efficient means for the economical production of recombinant proteins. however, there are still some challenges associated with high cell density cultivation (hcdc) techniques. a variety of strategies in several aspects including host design...

Various mesenchymal stem cells as easily accessible and multipotent cells can share different essential signaling pathways related to their stemness ability. Understanding the mechanism of stemness ability can be useful for controlling the stem cells for regenerative medicine targets. In this context, OMICs studies can analyze the mechanism of different stem cells properties or stemness ability...

Journal: :Acta neurochirurgica. Supplement 2005
M U Schuhmann G Heine M Skardelly M Jaeger H Selle

Proteomics and peptidomics are different and supplemental to genomics, since in contrast to the basically constant genome - the proteome and peptidome are dynamic, constantly changing, and complex networks. Proteomics is traditionally linked to 2D-gel electrophoresis techniques. Concerning peptidomics, three different approaches are currently available, all using mass spectrometry as a key elem...

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