In the process of hematogenous cancer metastasis, tumor cells (TCs) must shed into the blood stream, survive in the blood circulation, migrate through the vascular endothelium (extravasation) and proliferate in the target organs. However, the precise mechanisms by which TCs penetrate the endothelial cell (EC) junctions remain one of the least understood aspects of TC extravasation. This questio...

A multiplexed hollow fiber flow field-flow fractionation (MxHF5) is introduced to increase throughput of an HF5 channel system for semi-preparative purposes. HF5, a cylindrical version of the flow field-flow fractionation (FlFFF) operated with a porous, hollow fiber membrane by controlling the ratio of radial and axial flow rates, is capable of fractionating proteins, cells, and macromolecules ...

In this research, a pilot study and analysis of an innovative multi-channel photovoltaic/thermal (MCPV/T) system in a geographic location (35° 44' 35'' N, 50° 57' 25'' E) has been carried out. This system consists of integrating a photovoltaic panel and two PV/T heat-sink converters. The total electrical, exergy and energy efficiencies of the system at air flow rate of 0.005 kg/s and radiation ...

Visual motion, such as radial optic flow, is an important cue for perceiving direction during ego-motion. Several previous studies have reported that the perceived speed of a radial optic flow is underestimated when the represented ego-motion direction between radial optic flow and non-visual (such as vestibular or/and proprioceptive) information is congruent. In the present study, we examined ...

Thirteen repetitions of a cross-channel transect in the Khuran Channel within the Strait of Hormuz allowed the description of the mean flow and semidiurnal tidal properties of a north-south transect. Water velocity profiles were obtained with a 614.4 kHz TRDI Work Horse Broadband ADCP along this 3.3 km long transect on 10 October 2014, the third day of secondary spring tide. The M2, M4 and M6 f...

In this work we investigate the interplay between flow and boundary condition effects on the orientation field of a thermotropic nematic liquid crystal under flow and confinement in a microfluidic device. Two types of experiments were performed using synchrotron small-angle X-ray-scattering (SAXS). In the first, a nematic liquid crystal flows through a square-channel cross section at varying fl...

hydraulic simulation of water flow in irrigation canals may reveal management shortcomings and help managers find solutions to them. hydraulic simulation models can be appropriate tools for understanding hydraulic behavior of irrigation systems. in the present study, the steady state hec-ras model was tested and compared with the mike 11 unsteady state model. a secondary irrigation canal in the...

In this work, we applied Chebychev spectral collocation method to analyze the unsteady two-dimensional flow of nanofluid in a porous channel through expanding or contracting walls with large injection or suction. The solutions are used to study the effects of various parameters on the flow of the nanofluid in the porous channel. From the analysis, It was established that increase in expansion r...