The development of new chemical engineering design tools is essential for the implementation of the latest technology in the manufacture of chemical and other products. The focus of this paper is on process systems engineering (PSE) methods and tools, and especially on how such PSE methods and tools can be applied to speed up or support systematic bioprocess development at miniature scale. In t...

We explore the effects that different reactor types have on Spiky-RBN AChem systems, looking at mass conserving and flow reactors. To assist in analysing the behaviour we introduce an activity measure based on possible system state changes as a result of changes in particle properties. This leads to a discussion on approaches to engineering complex systems towards specific goals.

Production in Fed-Batch Reactor of Bacillus subtilis LipaseA Immobilized on its own Producer Saccharomyces cerevisiae Cells Lucia Paciello, Carmine Landi, Jesus Zueco, Palma Parascandola Department of Industrial Engineering, University of Salerno, via Ponte Don Melillo, 84084 Fisciano, Salerno, Italy Department of Microbiology, University of Valencia, Avda Vicente Andrès Estelles 46100, Burjass...

A three-dimensional bio-reactor model of exploitative competition of two predator organisms with inhibition responses for the same renewable organism with reproductive properties is considered. By using a Lyapunov function and the center manifold theorem the global stability, the existence of Hopf bifurcation and limit cycles are proved. This result is useful in understanding the nonlinear osci...

Hydrothermal Carbonization of Biomass: Design of a Batch Reactor and Preliminary Experimental Results Luca Fiori*, Daniele Basso, Daniele Castello, Marco Baratieri a University of Trento, Department of Civil, Environmental and Mechanical Engineering, via Mesiano, 77 – 38123 Trento, Italy b Free University of Bolzano, Faculty of Science and Technology, Piazza Università 5 – 39100 Bolzano, Italy ...

Institute of Nuclear and New Energy Technology, Collaborative Innovation Centre of Advanced Nuclear Energy Technology, Key Laboratory of Advanced Reactor Engineering and Safety of Ministry of Education, Tsinghua University, Beijing 100084, China; [email protected] (Y.P.); [email protected] (Z.Z.); [email protected] (Y.D.); [email protected] (X.H.) * C...

In this study, the homogeneity of the continuum model of a fixed bed reactor operated in steady state and unsteady state systems for lean CH4 oxidation is investigated. The steady-state fixed bed reactor system was operated under once-through direction, while the unsteady-state fixed bed reactor system was operated under flow reversal. The governing equations consisting of mass and energy balan...

Heat and mass transfer problem in a fixed-bed tubular reactor is one of the major concerns in the chemical engineering. The two dimensional axial plug flow model was used for a water gas shift reactor to compare heat conduction or mass diffusion with convective effect. In the case of fast fluid flow in highly permeable catalyst-bed, convective heat transfer was dominant compared to heat conduct...

This work builds on our prior results to develop novel control structure design principles for integrated plants featuring multiple time scale dynamics. Specifically, the concept of self-optimizing control can be used to identify the variables that must be controlled to achieve acceptable economic performance during plant operation. This approach does not, however, provide guidelines on control...