We report our experience with high resolution microarray analysis in infants and young children with developmental disability and/or aberrant behavior enrolled at the Centro Ann Sullivan del Peru in Lima, Peru, a low income country. Buccal cells were collected with cotton swabs from 233 participants for later DNA isolation and identification of copy number variation (deletions/duplications) and...

AMPTEK INC. 14 DeAngelo Drive, Bedford, MA 01730-2204 U.S.A. APPLICATIONS • X-Ray Fluorescence • Thin-film Analysis • RoHS/WEEE Analysis • Teaching and Research • Art and Archaeology • Process Control • X-ray Tube Characterization FEATURES • Fundamental parameters (FP) • Analysis with or without standards • General bulk and thin-film analysis • Analyze up to 40 elements • Supports all Amptek de...

■ 3 magnetic field channels and 3 acceleration channels ■ ±2/±4/±8/±12 gauss dynamically selectable magnetic full-scale ■ ±2/±4/±6/±8/±16 g dynamically selectable linear acceleration full-scale ■ 16-bit data output ■ SPI / I2C serial interfaces ■ Analog supply voltage 2.16 V to 3.6 V ■ Power-down mode / low-power mode ■ Programmable interrupt generators for freefall, motion detection and magnet...

Determining what proportion of the public has completed an advance directive and which population subgroups complete or do not complete such a directive is crucially important for planning purposes. Our research objective was to examine and compare advance directive completion, intention to complete, and noncompletion rates among citizens of one Canadian province. A telephone survey was conduct...

The primary goal was to specify the impact of scaffolding and overhearing on young children's use of the spatial terms between and middle. Four- and five-year-old children described the location of a mouse hidden between two furniture items in a dollhouse with assistance from a parent. Children's use of between and middle increased significantly across trials, and in concert, parents' directive...

OBJECTIVES To report doctors' views about the European Working Time Directive ('the Directive'). DESIGN Survey of the medical graduates of 2002 (surveyed in 2013-2014). PARTICIPANTS Medical graduates. SETTING UK. MAIN OUTCOME MEASURES Questions on views about the Directive. RESULTS The response rate was 64% (2056/3196). Twelve per cent of respondents agreed that the Directive had bene...

Genome-wide association studies have identified several common single nucleotide polymorphisms (SNP) associated with an increased risk of colorectal cancer (CRC), although they have failed to identify any recessively acting alleles that contribute to disease risk. However, two recent studies have suggested that inbreeding and runs of homozygosity (ROH) increase the risk of developing cancer, pe...

This Article traces the origins of the Database Directive and asks whether the Directive is a model that should be applied at the international level. Part I examines the background to the Directive. Such an examination is pertinent because the Commission went from a position in 1988 of limiting its proposal to copyright protection, to one of a “copyright plus” approach in 1992. Part II reviews...