BACKGROUND Most of the androgen replacement therapies were based on serum testosterone and without measurements of total androgen activities. Whether those with low testosterone also have low levels of androgen activity is largely unknown. We hence examined the association between testosterone and androstanediol glucuronide (AG), a reliable measure of androgen activity, in a nationally represen...

Mean serum testosterone concentration in the 27-day-old prepubertal Holtzman rat was 0\m=.\25ng/ml, much lower than that observed in the adult male, 5\m=.\5ng/ml. Within 15 min after the intravenous injection of rat LH (in a dose of 400 ng-equiv. NIH-LH-S1/100 g body weight) serum testosterone concentration in the prepubertal rat increased approximately fivefold. Maximal elevation of serum test...

Despite its association with vascular events such as myocardial and cerebral infarction, polycythemia vera (PV) is characterized by low serum total cholesterol levels. Because several sex hormones are derived from cholesterol, statins may induce hypogodanism in male patients. Therefore, we assessed the relationship between serum total cholesterol and sex hormone levels according to gender. Medi...

AIM To investigate the relationships of serum testosterone, insulin-like growth factor (IGF)-1 and IGF-binding protein (IGFBP)-3 levels with prostate cancer risk and also with known prognostic parameters of prostate cancer in Korean men who received radical retropubic prostatectomy (RRP) for clinically-localized prostate cancer. METHODS Serum levels of total testosterone, free testosterone, I...

Background: Aging in men causes a gradual decline in endogenous testosterone levels, which may have detrimental effects on their health status. Testosterone deficiency is thought to promote atherosclerosis by modulating lipid metabolism. Therefore, this study was conducted to evaluate the serum testosterone level and its correlation with lipid profile in men aged ≥60 years old. Methods: All el...

effect of propylthiouracil (ptu)-induced hypothyroidism during the prepubertal period, at a dose of oneg per kg of the diet, on serum testosterone level and seminal characteristics of fars indigenous chickens wasstudied. ptu was fed between 7th to 13th weeks of age and semen was collected at weekly intervals, starting at 21st week of age and continued for seven weeks. the effect of ptu treatmen...