نتایج جستجو برای: sox 9
تعداد نتایج: 484897 فیلتر نتایج به سال:
development. Proc. Natl. Acad. Sci. U. S. A. 90, 3368–3372 6 Vidal, V.P. et al. (2001) Sox9 induces testis development in XX transgenic mice. Nat. Genet. 28, 216–217 7 Zhang, J. et al. (1999) In vitro binding and expression studies demonstrate a role for the mouse Sry Q-rich domain in sex determination. Int. J. Dev. Biol. 43, 219–227 8 Capel, B. et al. (1993) Circular transcripts of the testis-...
In osteoarthritis (OA), activated synoviocytes and articular chondrocytes produce pro-inflammatory cytokines, such as IL-1β, that promote chondrocyte apoptosis and activate the NF-κB signaling pathway to induce catabolic factors. In this study, we examined the anti-inflammatory and anti-apoptotic effect of baicalein on IL-1β signaling and NF-κB-regulated gene products in rat chondrocytes. Rat c...
The aim of this study was to characterize the anti-inflammatory mode of action of botanical extracts from rosehip (Rosa canina), willow bark (Salix alba), and nettle leaf (Urtica dioica) in an in vitro model of primary canine articular chondrocytes. Methods. The biological effects of the botanical extracts were studied in chondrocytes treated with IL-1β for up to 72 h. Expression of collagen ty...
Objectives. To investigate whether high glucose-induced oxidative stress is implicated in apoptosis of rat nucleus pulposus cells (NPCs) and abnormal expression of critical genes involved in the metabolic balance of extracellular matrix (ECM). Methods. NPCs were cultured with various concentrations of glucose to detect cell viability and apoptosis. Cells cultured with high glucose (25 mM) were ...
Objectives: To perform a pilot hypothesis generating study of neoadjuvant docetaxel, estramustine, and androgen deprivation therapy for high-risk patients prior to radical prostatectomy. Patients and Methods: Twenty-eight patients received 4 cycles of docetaxel and estramustine administered on an every three week schedule in combination with androgen deprivation therapy (LHRH analog and bicalut...
SOX4 has been reported to be abnormally expressed in many types of cancer, including melanoma. However, its role in cell proliferation and metastasis remains controversial. In this study, SOX4 was downregulated or overexpressed in A375, A2058 and A875 melanoma cells by siRNA or lentivirus transfection, respectively. Cell metastasis was observed by Transwell assay. In an aim to elucidate the und...
The Y-box binding protein 1 (YB-1) is upregulated in many human malignancies including glioblastoma (GBM). It is also essential for normal brain development, suggesting that YB-1 is part of a neural stem cell (NSC) network. Here, we show that YB-1 was highly expressed in the subventricular zone (SVZ) of mouse fetal brain tissues but not in terminally differentiated primary astrocytes. Conversel...
The Y-box binding protein 1 (YB-1) is upregulated in many human malignancies including glioblastoma (GBM). It is also essential for normal brain development, suggesting that YB-1 is part of a neural stem cell (NSC) network. Here, we show that YB-1 was highly expressed in the subventricular zone (SVZ) of mouse fetal brain tissues but not in terminally differentiated primary astrocytes. Conversel...
Compliance with the Sarbanes–Oxley Act of 2002 (SOX) has been hampered by the lack of implementation details. This article argues that IT departments that have implemented ten categories of IT controls provided by the International Standards Organization (ISO 17799) will be well on their way toward SOX compliance. A side-by-side comparison of the 124 control components of the ISO Standard and t...
نمودار تعداد نتایج جستجو در هر سال
با کلیک روی نمودار نتایج را به سال انتشار فیلتر کنید