BACKGROUND Glucose-6-phosphate-dehydrogenase-deficiency (G6PDd) is a major risk factor for primaquine-induced haemolysis. There is a need for improved point-of-care and laboratory-based G6PD diagnostics to unsure safe use of primaquine. METHODS G6PD activities of participants in a cross-sectional survey in Bangladesh were assessed using two novel quantitative assays, the modified WST-8 test a...

Sera from patients being treated with phenytoin were analyzed for the drug by spectrophotometry, gas chromatography, radioimmunoassay, enzyme immunoassay, and liquid chromatography. The essay values obtained were intercompared statistically. Enzyme immunoassay and liquid chromatography appear to be attractive alternatives to the more traditional methods of spectrophotometry and gas chromatograp...

Various aspects of application of derivative spectrophotometry in chemical analysis and in investigations of equilibria and kinetics of reactions are scrutinized. The presented paper provides useful information about state-of-the-art and possibilities offered by derivative spectrophotometry in pharmaceutical, clinical or environmental fields of analysis.

Ultraviolet spectrophotometry has been successfully used for the qualitative as well quantitative determination of various phytoconstituents. For phytoconstituents in extract by ultraviolet spectrophotometry, absorbance at specific wavelength is measured. As a mixture number constituents, different constituents same along with compound interest can occur giving wrong interpretation observed dat...

Three simple and rapid spectrophotometric methods were developed for detection and trace determination of benzophenone (the main impurity) in phenytoin bulk powder and pharmaceutical formulations. The first method, zero-crossing first derivative spectrophotometry, depends on measuring the first derivative trough values at 257.6 nm for benzophenone. The second method, zero-crossing third derivat...

A sensitivity comparison was made between conventional atomic absorption spectrophotometry (AAS) and conventional molecular absorption spectrophotometry (MAS) for the serum trace metals, copper, iron, and zinc. The sensitivity aspect considered was absorbances was obtained for concentrations in the solutions analyzed using unit lightpaths of 1 cm and 10 cm for MAS and AAS, respectively. A disti...

In this research, the dinuclear Zn(ii) complex of anthracene based tripodal tetramine Zn2L was synthesized, and its sensing abilities towards anions was investigated using the indicator displacement assay (IDA) approach with four complexometric indicators: pyrocatechol violet (PV), bromopyrogallol red (BPG), methylthymol blue (MTB) and xylenol orange (XO). UV-vis spectrophotometry results indic...

Aim to develop a method for standardization of licorice herb.
 Material and methods. The material the study was herb harvested in Alekseevka settlement Samara Region (2021), Tatarskaya Kargala village Sakmarskiy area Orenburg (2017), Derzhavinsk city Republic Kazakhstan (2018), Bol'shaya Chernigovka Bol'shchernigovsk (2019), commercial sample root raw from AO "Krasnogorskleksredstva". In a...

THE INITIAL STUDIES BY WILLIS (2, 3) and the more recent work of Zettner and Seligson (i) and others (4-7, 9-11) have proven the utility of atomic absorption spectrophotometry (AAS) in the clinical laboratory. However, until very recently there has been very little if any published information dealing with normal serum calcium values by atomic absorption spectrophotometry (11). The primary purp...