resolution of binary mixtures of theophylline (theo), montelukast (mkst) and loratadine (lora) with minimum sample pretreatment and without analyte separation has been successfully achieved by multivariate spectrophotometric calibration, together with partial least-squares (pls-1), principal component regression (pcr) and hybrid linear analysis (hla). data of analysis were obtained from uv–vis ...

Three murine leukemia lines resistant to cÃo-diamminedichloroplatinum(II) and one line resistant to diaminocyclohexane (DACH) platinum(II) complexes were compared to their platinum-sensitive parent lines to determine whether differences in net platinum accumulation were related to the resistant phenotype. The ciVdiamminedichloroplatinum(II}-resistant lines (L1210PIR4, L1210DDPS, P388PtR4) and t...

The direct chelation-extraction method, originally developed by Hessel (1968) for blood lead analysis, has been successfully applied to urinalysis for manganese. The analyses of 35 urine samples containing up to 100 microgram/1 of manganese from manganese-exposed workers showed that the data obtained by this method agree well with those by wet digestion-flame atomic absorption spectrophotometry...

the acid-base equilibrium of lorazepam was studied by means of potentiometry andmultiwavelengths spectrophotometry. the stoichiometric equilibrium constants were determinedat 25 °c and constant ionic strength 0.1 mol l-1 (nacl). the acidity constants pk1=1.58±0.05and pk2=11.67±0.07 were found by potentiometry, and pk1=1.54±0.02 and pk2=11.61±0.03 bymulti-wavelengths spectrophotometry. potentiom...

Chrysophanol (Chry, Figure 1), 1,8-dihydroxy-3methylanthraquinone, is a free anthraquinone compound and a secondary metabolite of medicinal plant rhubarb. Chry has been reported to have many pharmacological effects such as anti-inflammatory activity [1], anti-microbial activity [2] and anti-cancer action [3]. Therefore, the detection of Chry is quite important and interesting. Until now, variou...