Indirect methods play an important role in the determination of nuclear reaction cross sections that are hard to measure directly. In this paper we investigate the feasibility of using the so-called surrogate method to extract neutron-capture cross sections for low energy compound-nuclear reactions in spherical and near-spherical nuclei. We present the surrogate method and develop a statistical...

Environmental epidemiologic studies are often hierarchical in nature if they estimate individuals’ personal exposures using ambient metrics. Local samples are indirect surrogate measures of true local pollutant concentrations which estimate true personal exposures. These ambient metrics include classical-type nondifferential measurement error. The authors simulated subjects’ true exposures and ...

We develop a variant of multiclass logistic regression that achieves three properties: i) We minimize a non-convex surrogate loss which makes the method robust to outliers, ii) our method allows transitioning between non-convex and convex losses by the choice of the parameters, iii) the surrogate loss is Bayes consistent, even in the non-convex case. The algorithm has one weight vector per clas...

As a starting point of this paper we present a problem from mammographic image processing. We show how it can be formulated as an optimal control problem for PDEs and illustrate that it leads to penalty terms which are non-standard in the theory of optimal control of PDEs. To solve this control problem we use a generalization of the conditional gradient method which is especially suitable for n...

In this paper we investigate a test for the identification of nonlinear dependence in time series against more general “nulls” than mere “independence”. The approach is based on a combination of an entropy dependence metric, possessing many desirable properties and used as a test statistic, together with a suitable extension of surrogate data methods, a class of Monte Carlo based tests introduc...

Nanoindentation involves probing a hard diamond tip into a material, where the load and the displacement experienced by the tip is recorded continuously. This load-displacement data is a direct function of material's innate stress-strain behavior. Thus, theoretically it is possible to extract mechanical properties of a material through nanoindentation. However, due to various nonlinearities ass...

Background Myocardial oedema is a consequence of injury during ST segment elevation myocardial infarction (STEMI). T2 weighted short tau inversion recovery (T2w STIR) is widely used for oedema assessment on CMR. No consensus exits for which threshold/ contouring method should be used for the quantification of the area of myocardial oedema as a surrogate endpoint in clinical trials. This study i...

Environmental epidemiologic studies are often hierarchical in nature if they estimate individuals' personal exposures using ambient metrics. Local samples are indirect surrogate measures of true local pollutant concentrations which estimate true personal exposures. These ambient metrics include classical-type nondifferential measurement error. The authors simulated subjects' true exposures and ...