Aim. To substantiate the optimal composition of base semisolid dosage form with thick extract feverfew (Tanacetum parthebased on structural-mechanical, textural, adhesive and microscopic studies. Materials methods. The study objects were samples a various gelling agents reference drug “Irikar”. In course research, complex structural-mechanical methods analysis used. Results discussion. studies ...

Starvation-induced differentiation of the slime mould Physarum polycephalum is accompanied by continuous methylation of DNA. No stable changes in the overall level of DNA methylation are evident, but a gene known to be transcribed specifically during differentiation is subject to increased methylation. Inhibitors of DNA methylation preclude differentiation of P. polycephalum, although they are ...

We have studied the role of the nuclear matrix in DNA replication in a naturally synchronized eucaryote, Physarum polycephalum. When P. polycephalum. When P. polycephalum macroplasmodia were pulse labeled with 3H-thymidine, the DNA remaining tightly associated with the matrix was highly enriched in newly synthesized DNA. This enrichment was found both in nuclei that had just initiated DNA repli...

The manipulation of biological substrates is becoming more popular route towards generating novel computing devices. Physarum polycephalum is used as a model organism in biocomputing because it can create ‘wires’ for use in hybrid circuits; programmable growth by manipulation through external stimuli and the ability withstanding a current and its tolerance to hybridisation with a variety of nan...

Microbial fuels cells (MFCs) are bio-electrochemical transducers that generate energy from the metabolism of electro-active microorganisms. The organism Physarum polycephalum is a slime mould, which has demonstrated many novel and interesting properties in the field of unconventional computation, such as route mapping between nutrient sources, maze solving and nutrient balancing. It is a motile...

The plasmodium of Physarum polycephalum is often used in the implementation of non-linear computation to solve optimization problems, and this organismal feature was not used in this analysis to compute perception and/or sensation in humans. In this paper, we focused on the Kanizsa illusion, which is a well-known visual illusion resulting from the differentiation-integration of the visual field...

introduction: tanacetum sonbolii (asteraceae) is an endemic species in iran. in the present study, we examined the effects of tanacetum sonbolii hydroalcoholic extract on the formalin test in mice. methods: 126 swiss albino mice weighing 230-280g were used as subjects. the formalin test was performed on two control groups (marked as intact and saline groups n = 6 in each group) and an experimen...

A plasmodium of acellular slime mould Physarum polycephalum is a large single cell with many nuclei. Presented to a configuration of attracting and repelling stimuli a plasmodium optimizes its growth pattern and spans the attractants, while avoiding repellents, with efficient network of protoplasmic tubes. Such behaviour is interpreted as computation and the plasmodium as an amorphous growing b...

BACKGROUND Sporadic Alzheimer's Disease (SAD) is caused by genetic risk factors, aging and oxidative stresses. The herbal extract of Rosa canina (R. canina), Tanacetum vulgare (T. vulgare) and Urtica dioica (U. dioica) has a beneficial role in aging, as an anti-inflammatory and anti-oxidative agent. In this study, the neuroprotective effects of this herbal extract in the rat model of SAD was in...