background: tricyclic antidepressants (tcas) poisoning is the most common poisoning in the poisoning emergency department of noor hospital, isfahan, iran. the objective of this study was to compare qrs interval duration with ravr³3mm and r/savr³ 0.7 in predicting: serious complications of acute tca toxicity. methods and materials: this study was descriptive – analytic and prospective cohort. tc...

To determine how soil properties influence nanoparticle (NP) fate, bioavailability and toxicity, this study compared the toxicity of nano zinc oxide (ZnO NPs), non-nano ZnO and ionic ZnCl2 to the earthworm Eisenia fetida in a natural soil at three pH levels. NP characterisation indicated that reaction with the soil media greatly controls ZnO properties. Three main conclusions were drawn. First ...

teucrium polium l. (tp) is widely used in traditional medicine of many countries including iran. there are various reports about pharmacological properties of tp such as calcium antagonist, anti- ulcer, anti – diabetic. there are a few reports about possible toxicological effects of this plant. in the present study we designed to evaluate the subchronic toxicity of teucrium polium total extract...

objective(s) ocimum basilicum l. is widely used in folk medicine of many countries including iran. both o. basilicum and its oil extract have received considerable attention for their potential medicinal properties, but there are a few reports about possible toxicity of this plant. therefore, in the present study, acute and subchronic toxicity of o. basilicum hydroalcohlic extract have been eva...

the purpose of this work is to develop robust and interpretable quantitative structure”activity relationship (qsar) models for assessing the aquatic toxicity of phenols using a combined set of descriptors encompassing the logp and recently developed variables (monconn-z variables). the used dataset consists of 250 chemicals with toxicity data to the ciliate tetrahymena pyriformis. for each com...

      In the present study, aqueous solutions of some copper-complexing ligands were screened for their cytotoxicity using brine shrimp lethality test. Among the ligands tested, diacetyl-bis(N4-methylthiosemicarbazones) (ATSM) proved to be the most safe and non-toxic compound (2% lethality at 10 ppm), while pyruvaldehyde Bis(N4-methyl)thiosemicarbazone (P...

Antipredator defenses and warning signals typically evolve in concert. However, the extensive variation across taxa in both these components of predator deterrence and the relationship between them are poorly understood. Here we test whether there is a predictive relationship between visual conspicuousness and toxicity levels across 10 populations of the color-polymorphic strawberry poison frog...

Objective(s): The current study aimed to investigate the relationship of genetic polymorphism and plasma methotrexate (MTX) levels, toxicity experience and event free survival (EFS) in pediatric acute lymphoblastic leukemia (ALL). Materials and Methods: The study included 74 ALL patients. Polymerase chain reaction and genotyping of methy...