The aim of this study is to formulate and optimize novel transfersome formulations for pulmonary drug delivery. Transfersome (F1 – F18) were prepared by a thin-film method using three phospholipids (Soya phosphatidylcholine (SPC), Dimyristoly (DMPC) Hydrogenated soya (HSPC)), in combination with different surfactants (Tween 80, Span 80 20) or without cholesterol, employing Beclomethasone diprop...

<span lang="EN-US">Skin aging is a complex biological process caused by intrinsic and extrinsic factors. There are various approaches to preventing skin aging, one of which using herbal nanocosmetics. This narrative review aims determine the natural ingredients, type nanoformulations, its effects nanocosmetics prevent aging. The method used in this study was searching for articles related...

Burn injuries can have a lasting effect on people’s quality of life, as they negatively impact their physical and mental health. Then, are likely to suffer psychological problems result. A serious problem is that deep burns more challenging treat due slow healing rate susceptibility microbial infection. Conventional topical medications used for burn treatment sometimes ineffective because canno...

Human papillomavirus (HPV) cause common warts, laryngeal papilloma and genital condylomata and might lead to development of cervical cancer. Lactoferrin (LF) is a member of the transferrin family, which has antiviral activity against HPV-16. LF is an important player in the defense against pathogenic microorganisms and has also been shown to have activity against several viruses including herpe...

The aim of this study was firstly to refine a rat model of arthritis, the adjuvant arthritis (AA) model, by studying the time course of the disease, introducing new evaluation methods such as haematological and biochemical parameters in order to identify the main stages of the disease. An optimisation of treatment schedule and evaluation criteria was developed. This refinement provided novel no...

Dear Friends, We all are well known with a fact of benefits of novel topical drug delivery systems, namely avoidance of hepatic first-pass metabolism, thus improving drug bioavailability, decreasing dosing frequency, and improving patient compliance. Regardless of the enormous investigations in topical and transdermal drug delivery systems, still stratum corneum is known as a major obstacle whi...

Phytomedicines are used worldwide by human being from ancient times. Herbal drugs are becoming more popular in the modern world for their application to cure variety of diseases with less toxic effects and better therapeutic effects. However these medicines suffer from certain limitation such as toxicity, stability issues, poor bioavailability and patient compliance. To minimize these problems ...

Human papillomavirus (HPV) cause common warts, laryngeal papilloma and genital condylomata and might lead to development of cervical cancer. Lactoferrin (LF) is a member of the transferrin family, which has antiviral activity against HPV-16. LF is an important player in the defense against pathogenic microorganisms and has also been shown to have activity against several viruses including herpe...