BACKGROUND Dolphin® visual treatment objective (VTO) prediction software is routinely utilized by orthodontists during the treatment planning of orthognathic cases to help predict post-surgical soft tissue changes. Although surgical soft tissue prediction is considered to be a vital tool, its accuracy is not well understood in tow-jaw surgical procedures. The objective of this study was to quan...

PURPOSE To develop an in-house software program that is able to calculate and generate the biological dose distribution and biological dose volume histogram by physical dose conversion using the linear-quadratic-linear (LQL) model. MATERIAL AND METHODS The Isobio software was developed using MATLAB version 2014b to calculate and generate the biological dose distribution and biological dose vo...

In regional hyperthermia extensive numerical simulations are required for optimizing individual cancer therapy treatments. To take full advantage of such simulations a therapy planning system is needed. In this paper we discuss a new hyperthermia planning system, focussing on its visualization and 3D-interaction functionality. Our software, called HyperPlan, assists the whole treatment planning...

Electrochemotherapy uses electroporation for enhancing chemotherapy. Electrochemotherapy can be performed using standard operating procedures with predefined electrode geometries, or using patient-specific treatment planning to predict electroporation. The latter relies on realistic computer models to provide optimal results (i.e. electric field distribution as well as electrodes' position and ...

Three-dimensional (3D) treatment planning refers to the use of software and hardware tools to design and implement more accurate and conformal radiation therapy. This is a major advance in oncology that should lead to the reduction of treatment-associated morbidity and facilitate safe dose escalation for many tumor sites. This technology affords the incorporation of physiologic and anatomic inf...

Improvements in software processes can improve software quality, cost, and on-time delivery. Supplementing strategic software release planning with fine grain operational planning provides project managers the tools and abilities to make timely decisions affecting the project. Strategic planning of software releases is accomplished by the assignment of requirements to releases on a strategic le...

Risk is not always avoidable, but it is controllable. The aim of this paper is to present new techniques which use the stepwise regression analysis to model and evaluate the risks in planning software development and reducing risk with software process improvement. Top ten software risk factors in planning software development phase and thirty control factors were presented to respondents. This...

Along with innovative ideas for treating non static tumours comes the need of a 4D supporting treatment planning software. The GSI code treatment planning for particles (TRiP) [1;2] has recently been extended to 4D capabilities (TRiP4D) [3]. The status of TRiP4D has proceeded to a level which allows the first four dimensional uncertainty simulations. The sum of all uncertainties present at trea...

The overall penumbra is usually defined as the distance, p20–80, separating the 20% and 80% of the dose on the beam axis at the depth of interest. This overall penumbra accounts also for the fact that some photons emitted by the distal parts of the source are only partially attenuated by the collimator. Medulloblastoma is the most common type of childhood brain tumor and often spreads to the sp...