background: application of different sources of fatty acids and their effect on ovarian performance is a current issue in animal science and research centers. objectives: the purpose of this study was to determine the effect of different fatty acids in close-up period on population and size of follicles and measuring blood parameters related to the energy state of the body after calving of lact...

Cholera toxin (CT) is an archetypal bacterial toxin that binds with a high affinity to the receptor ganglioside GM1 on the intestinal epithelial surface and that causes the severe watery diarrhea characteristic of the disease cholera. Blockage of the interaction of CT with the GM1 receptor is an attractive approach for therapeutic intervention. We report here that crude bile prevents the intera...

The aim of this work was to explore the ability of free arachidonic acid, palmitic acid and the unsaturated fatty acids oleic acid and docosahexaenoic acid to modify calcium homeostasis and mitochondrial function in rat pachytene spermatocytes and round spermatids. In contrast to palmitic acid, unsaturated fatty acids produced significant increases in intracellular calcium concentrations ([Ca2+...

The induction of autophagy usually requires the activation of PIK3C3/VPS34 (phosphatidylinositol 3-kinase, catalytic subunit type 3) within a multiprotein complex that contains BECN1 (Beclin 1, autophagy related). PIK3C3 catalyzes the conversion of phosphatidylinositol into phosphatidylinositol 3-phosphate (PtdIns3P). PtdIns3P associates with growing phagophores, which recruit components of the...

The influence of lipids on gap-junction-mediated intercellular communication (i.e., metabolic cooperation) between Chinese hamster V79 cells was investigated. Unsaturated free fatty acids (oleate, linoleate, linolenate, palmitoleate, myristoleate, and arachidonate) inhibited metabolic cooperation between 6-thioguanine-resistant, hypoxanthine guanine phosphoribosyltransferase-deficient and 6-thi...

Shortenings are a mixture of one or more vegetable edible oil with partial hydrogenation in mixed with or without animal fat. In this study, three formulations of shortenings, with the best commercial and technological properties were prepared. Increasing consumption of shortenings at the human daily diet, with low adverse coronary effects in human daily diet, three formulations prepared using ...

dietary fatty acids play a critical role in modulation of airway inflammation in asthma. this study was conducted to compare dietary intakes of essential fatty acids and serum levels of inflammatory factors in asthmatic and healthy adults, and to examine the potential relationship between inflammatory markers and dietary fatty acids. in this case-control study, 47 asthmatic patients (26 males a...

The procedures implemented in the production of functional foods of animal origin should be based on the scientifically verified new knowledge comprising the entire food chain. Possible physiological and psychological effects of such foods on humans should not be neglected. Although the human genome did not change since the Palaeolithic, however the nutritional habits and way of life of modern ...

The ciliate Tetrahymena pyriformis synthesizes a wide variety of saturated and unsaturated fatty acids. Variations in growth temperature or the addition of sterols such as cholesterol or ergosterol alter the proportions of a number of unsaturated fatty acids. The pattern of substitution is complex when examined on the basis of individual fatty acids. A straightforward explanation is possible, h...

Background Background: The fatty acid composition of the sperm membrane changes drastically during spermatogenesis and may be key to its function. Previous data has shown that intake of long chain poly-unsaturated fatty acids can change the fatty acid composition of tissues, including testes and sperm. However, whether these changes in composition translate into changes in semen quality or male...