Effective interaction between mucoadhesive drug delivery systems and mucin is the basis of effective local placement of drugs to play its therapeutic role after mucosal administration including vaginal use, which especially requires prolonged drug presence for the treatment of gynecological infectious diseases. Our previous report on phenylboronic acid-rich nanoparticles (PBNPs) demonstrated th...

BACKGROUND Recurrent urinary tract infection (RUTI) is defined as three episodes of urinary tract infection (UTI) in the previous 12 months or two episodes in the last six months. The main factors associated with RUTI in postmenopausal women are vesical prolapse, cystocoele, post-voidal residue and urinary incontinence, all associated with a decrease in oestrogen. The use of oestrogens to preve...

Background: White vaginal discharge is a physiological process in women, depicting various stages of the menstrual cycle, but when accompanied with an infection vagina or cervix, it can present as abnormal, excessive odour, irritation, and variation colour. Certain perceptions women lack their knowledge pertaining to genital hygiene play role on reproductive health. This study was taken up find...

Background: Normal vaginal delivery causes sexual dysfunction as well as urinary and fecal incontinence, which can threaten a person's quality of life. It is believed that pelvic floor muscle strength is the most important factor in improving sexual satisfaction and function and urinary control. Therefore, This study aimed to investigate the role of physiotherapy and pelvic floor exercises in r...

OBJECTIVE To support the practitioner in the diagnosis of vaginal atrophy and in the management of the related symptoms. OPTIONS The modalities of evaluation range from basic pelvic examination, examination of the vulva, and laboratory tests. OUTCOMES A comprehensive approach to the detection of vaginal atrophy and a discussion of available therapeutic and nontherapeutic options. EVIDENCE...

AIM To clarify the contribution of clinical and environmental factors and infection to the aetiology of vulvovaginitis in premenarchal girls, and to determine clinical indicators of an infectious cause. DESIGN It was necessary first to define normal vaginal flora. Cases were 50 premenarchal girls > 2 years old with symptoms of vulvovaginitis; 50 controls were recruited from girls in the same ...

background: hospital is a place to provide medical services. it is affected by noise pollution sources that can be associated with negative impacts on health and comfort status of the staff members and patients. the aim of this study was to measure noise levels in different wards of hospitals and to determine the irritation caused by noise among the hospital staff members in hamadan, iran. meth...

The authors carried out an evaluation of the genito-urinary syndrome of menopause, which is defined as a set of signs and symptoms associated with the reduction of estrogen and other sex steroids involving changes in labia maiora and minora, clitoris, vaginal vestibule, urethra and bladder, which create discomfort and are not better explained by another diagnosis. The syndrome may include, but ...

OBJECTIVE The objective of this study was to compare reproductive performance parameters for two protocols for estrus synchronization in dairy heifers in Germany. MATERIAL AND METHODS In the CIDR group (n=93) all heifers received a controlled intravaginal progesterone releasing insert (Eazi-Breed™ CIDR®; Pfizer Pharma GmbH; containing 1,38g of progesterone) on day 0. On day 7 these cows were ...

OBJECTIVE To estimate the accuracy of the clinical diagnosis of the three most common causes of acute vulvovaginal symptoms (bacterial vaginosis, candidiasis vaginitis, and trichomoniasis vaginalis) using a traditional, standardized clinical diagnostic protocol compared with a DNA probe laboratory standard. METHODS This prospective clinical comparative study had a sample of 535 active-duty Un...