bk virus (bkv) is a polyomavirus with seroprevalence in adults, ranging from 60 to 100%. it is considered as usual cause of renal dysfunction after the allograft renal transplantation nephropathy. potent immunosuppressive therapy in kidney transplantation can lower the rate of acute rejection. therefore, untreated bkv infections lead to kidney allograft dysfunction or loss. in order to estimate...

More than 70% of the general population worldwide has serological evidence of exposure to Polyomavirus hominis type 1, better known as BK virus (BKV). BKV infection typically occurs during childhood, without specific symptoms, followed by a state of nonreplicative infection in various tissues, with the urogenital tract as the principal site. Asymptomatic reactivation and low-level replication w...

During the last 10 years, polyoma BK-virus associated nephropathy (PVAN) has emerged as a serious complication in renal transplant recipients [1]. Due to the establishment of an accurate non-invasive screening procedure measuring polyomavirus BK-viraemia, BK-viruria and decoy cells in urine, PVAN can be diagnosed at early stages [2]. This allows for timely therapeutic intervention, which has si...

The Polyomaviridae family includes ubiquitous viruses with specific host spectra. Human polyomavirus BK (BKV) was discovered in 1971 and shortly after that became evident that around 80% of adults had anti-BKV antibodies. This raised important questions connected with its mode of transmission and pathogenesis. Nowadays they are still unclear (Sessa, 2008). Following primary infection, which is ...

Zika virus (ZIKV), an emerging flavivirus, has recently spread explosively through the Western hemisphere. In addition to symptoms including fever, rash, arthralgia, and conjunctivitis, ZIKV infection of pregnant women can cause microcephaly and other developmental abnormalities in the fetus. We report herein the results of ZIKV infection of adult rhesus macaques. Following subcutaneous infecti...