INTRODUCTION BKV nephropathy (BKN) causes kidney graft loss, whose specific diagnosis is invasive and might be predicted by the early detection of active viral infection. OBJECTIVE Determine the BKV-infection prevalence in late kidney graft dysfunction by urinary decoy cell (DC) and viral DNA detection in urine (viruria) and blood (viremia; active infection). METHODS Kidney recipients with ...

Polyoma BK virus (BKV) is frequently identified in the urine of bone marrow transplantation (BMT) patients with hemorrhagic cystitis (HC). However, viruria is common even in asymptomatic patients, making a direct causative role of BKV difficult to establish. This study prospectively quantified BK viruria and viremia in 50 BMT patients to define the quantitative relationship of BKV reactivation ...

BACKGROUND Although early monitoring of BK virus infection in renal transplant patients has led to improved outcomes over the past decade, it remains unclear whether monitoring for viremia is the best screening tool for BK virus nephropathy (BKVN). METHODS We conducted a retrospective review of the medical records of 368 renal transplant recipients who had a minimum of 18 months of posttransp...

Two polyomaviruses, BK virus (BKV) and JC virus (JCV), are ubiquitous in the human population, generally infecting children asymptomatically and then persisting in renal tissue. It is generally thought that reactivation leads to productive infection for both viruses, with progeny shed in the urine. Several studies have shown that the rate of JC viruria increases with the age of the host, but a ...

BACKGROUND BK nephropathy is an evolving challenge among kidney transplant recipients. Diagnosis of BK nephropathy depends on the presence of BK viral inclusions on renal biopsy. Most cases of BK nephropathy are preceded by BK viremia or viruria. CASE REPORT We report a case of BK nephropathy found on protocol renal transplant biopsy without associated BK viremia or viruria. CONCLUSIONS BK ...

Polyomavirus (PyV) infection usually persists without any symptoms in normal individuals. In immunocompromised patients including patients with systemic lupus erythematosus (SLE), PyV reactivation occurs with a high prevalence and can cause severe clinical complications. In this study, reactivation of six PyV [JC, BK, WU, KI, merkel cell (MC) and trichodysplasia spinulosa (TS)] was investigat...

This study investigated the occurrence of canine distemper virus (CDV) by evaluating the presence of viral RNA within urine samples of dogs from Uberlândia, MG, with clinical manifestations suggestive of infection by CDV by targeting the CDV N gene. Of the clinical samples collected (n=33), CDV viruria was detected in 45.5%. Five dogs died spontaneously; all had characteristic CDV-associated hi...

Viruria has been demonstrated in many human and animal viral infections (1, 2). Preliminary studies in mice and rats by Schultz and Neva (3) established that virus passes from blood to urine within 30 minutes after intravenous injection under the conditions of their experiments. This viruria was referred to as "immediate viruria" and was considered to be distinct from the viruria that occurs du...

Viruria has been demonstrated in many human and animal viral infections (1, 2). Preliminary studies in mice and rats by Schultz and Neva (3) established that virus passes from blood to urine within 30 minutes after intravenous injection under the conditions of their experiments. This viruria was referred to as "immediate viruria" and was considered to be distinct from the viruria that occurs du...