S t u d y s e l e c t i o n Published and unpublished studies were selected if they were randomized controlled trials (RCTs) of ≥ 1 year of duration in postmenopausal women; compared etidronate (using the intermittent cyclic method at 400 mg/d for 14 to 20 d, and then using calcium or vitamin D, or both) with placebo, calcium, vitamin D, or calcium plus vitamin D; and evaluated outcomes of frac...

multiple risk factors are introduced for multiple sclerosis (ms). recent studies have suggested a possible correlation between vitamin d deficiency and an increase risk of ms. this study was therefore undertaken to compare vitamin d levels in new cases of ms and their relatives as healthy controls. seventy five new diagnosed ms patients and 100 matched healthy controls among their relatives wer...

Background: Due to the interruption of the EHC pathway in NAFLD patients, we hypothesized that parenteral vitamin D supplementation is superior to oral in vitamin D insufficient patients with NAFLD. Therefore, this study aimed to compare the efficacy of oral and parenteral routes of vitamin D supplementation on serum 25(OH) vitamin D levels in patients with NAFLD. Methods: In this prospective ...

Colorectal cancer is the third most commonly occurring cancer in the United States and accounts for approximately 11% of cancer deaths. Many epidemiological studies have shown an association between dietary factors, including calcium and vitamin D, and the incidence of colon cancer. Recently the Calcium Polyp Prevention Study demonstrated that calcium supplementation can reduce the recurrence o...

introduction: vitamin d has an important role in maintaining human health. the main source of vitamin d production is skin exposure to sunlight. accordingly with the spread of apartment life culture, growth of industrial cities and the increase of air pollution; vitamin d deficiency and its implications is an important factor in the appearance of debilitating diseases in different age categorie...

Vitamin D deficiency is one of the major health problems that is unexpectedly prevalent in Iran. The ultraviolet (UV) rays of the sunlight are the most important source of vitamin D in humans. In contrast, environmental factors are one of the reasons for decrease in UV transmission to the earth which results in the reduction of vitamin D absorption. Since the role of environmental factors has b...