Identify the red cells morphological changes (Peripheral blood smear) due to altered haematopoiesis resulting from HIV infection and the pathogenesis of red cells morphological changes in human immunodeficiency virus (HIV). Blood was collected in a sterile EDTA containing tube and processed following our established laboratory protocol and by universal precaution as per the guideline of Nationa...

BACKGROUND White blood cell count is an independent risk factor for cardiovascular disease. Several lifestyle and metabolic factors such as cigarette smoking and obesity are known to be associated with an elevated white blood cell count. However, the joint effect of cigarette smoking and obesity on white blood cell count has not yet been fully described. METHODS We explored the joint effect o...

Rearrangement or translocation of the SCL gene is the most common genetic abnormality observed in human T-cell acute lymphocytic leukemia and results in the aberrant expression of SCL. To examine the oncogenic potential of this gene, an SCL-retrovirus was used to infect mouse bone marrow cells, which were then used to reconstitute C57/BL6 mice. Expression of SCL did not perturb the composition ...

Whereas many differential leukocyte count methods for high somatic cell count (SCC) milk from mastitic cows are available, only a few have been developed for low SCC milk. We have developed a flow cytometric differential leukocyte count method for low SCC milk. The procedure consists of 1) 1.5 ml of diluted milk sample (30%, vol/vol dilution with PBS), 2) centrifugation, 3) leukocyte labeling w...

The peripheral circulating white blood cell (WBC) or leukocyte count originate in the hematopoietic stem cells and develop along distinct differentiation in response to internal and external cues [1]. The total number of WBC in the circulation is given as the peripheral WBC count and proportion of the total number of WBC represented by differentiated granulocytes (neutrophils, eosinophils and b...

OBJECTIVE To investigate haematological variations and iron related changes in the serum of participants in a 1600 kilometre ultramarathon run. PARTICIPANTS Seven male and two female participants in a 1600 km foot race. METHODS Blood samples were obtained from the participants before, after four and 11 days of running, and at the end of the event. Samples were analysed by standard methods f...