Following an epidemiological survey of zoonotic cutaneous leishmaniosis (ZCL) in some villages of Badrood, a rural district north of the city of Natanz, central Iran, Phlebotomus (Phlebotomus ) papatasi Scopoli were found to be naturally infected with Leishmania (Leishmania) major zymodeme MON-26. Sandflies were collected and dissected biweekly from rodent burrows during sandfly season, Ap...

BACKGROUND The incidence of zoonotic cutaneous leishmaniasis (ZCL) makes it the most widespread parasitic disease in Tunisia and the Arab world. Yet, few studies have addressed its psychological and psychosocial effects. The purpose of this study was to examine the psychosocial impact of ZCL scars among Tunisian women. METHODS We conducted an exploratory study, we administered Revised Illness...

background: interest in tatera indica rodent arises mostly because it is believed that this species is survived among four subspecies reported from iran, two of which exist in khuzestan province. in addition, it might has a role as res­ervoir hosts of zoonotic cutaneous leishmaniasis in the transmission of leishmania major in some of the widespread asian foci including southwestern iran. method...

Background: Zoonotic cutaneous leishmaniasis (ZCL) due to Leishmania major is increasing in many parts of Iran. This disease originally is a disease found in gerbils. Leishmania parasites are transmitted by sandflies that live and breed in gerbil burrows. Nested PCR amplified Leishmania ITS1-5.8S rRNA gene in both main reservoir host “Rhombomys opimus” and in the “Phlebotomus papatasi” main vec...

b a ckground: zoonotic cutaneous leishmaniasis is a growing health problem in many rural areas of iran. rhombo mys opimus , the great gerbil, is the main animal reservoir of zcl in the northeast and central part of iran. the aim of the current study was to evaluate the rodenticidal effect of coumavec® (a mixture of coumatetralyl 0.5% and etofenprox 0.5%) on r. opimus under laboratory condition....

background: zoonotic cutaneous leishmaniasis (zcl) is an increasing public health problem in some endemic re­gions. horseradish peroxidase (hrp) conjugated rabbit anti- rhombomys opimus ( r. opimus ) ig is needed for im­munoblotting and elisa tests used to explore the immune response of the rodents against the sand fly saliva. in this study, the production of hrp conjugated rabbit anti- r. opim...

BACKGROUND In the northeast and central parts of Iran, Rhombomys opimus (great gerbil) is the primary reservoir host of zoonotic cutaneous leishmaniasis (ZCL). This study used both parasitological and molecular methods to identify Leishmania spp. and their different haplotypes that were circulating in the great gerbil populations in ZCL foci from northeastern Iran. METHODS A cross-sectional s...

Leishmaniasis is a zoonotic and vector-borne infectious disease that caused by the genus Leishmania belonging to trypanosomatid family. The protozoan parasite has digenetic life cycle involving mammalian host an insect vector. Leishmaniasisis worldwide public health problem falling under neglected tropical category, with over 90 endemic countries, approximately 1 million new cases 20,000 deaths...

BACKGROUND In human leishmaniasis Th1/Th2 dichotomy similar to murine model is not clearly defined and surrogate marker(s) of protection is not yet known. In this study, Th1/Th2 cytokines (IL-5, IL-10, IL-13 and IFN-γ) profile induced by purified CD4(+)/CD8(+) T cells in response to Leishmania antigens were assessed at transcript and protein levels in 14 volunteers with a history of self-healin...