hla-g is normally expressed on human trophoblast cells. it is a non-classical mhc molecule class i b. the role of hla-g in diabetic type 1 is not known. we investigated the role of ifn-β in induction hla-g expression on the monocyte derived dendritic cells (dc) in diabetes type 1. treatment of dendritic cell with ifn-β in vitro from diabetic patients (n=20) and normal subjects (n=20) resulted t...

background and objectives: the genus johrenia belongs to umbelliferae family and contains five species that are endemic to iran. johrenia paucijuga grows widely in the north-west, west and center of iran. so far, there has been no research about phytochemistry of j. paucijuga. in the present study, phytochemicals of the plants have been isolated and their structures have been elucidated. method...

by application of modern recombinant dna technology, especially the polymerase chain reaction (pcr)/dot-blot hybridization techniques, we have investigated the molecular basis of β-thalassemia from four different regions of iran: central, south-east, south and north. in this study, the dna samples were isolated from patients and for the identification of the mutations, the 6 oligonucleotide pro...

Background: The carbonyl group at position 2 of N-acetylisatin behaves as an amide which is more susceptible to nucleophilic attack via ring-opening in the presence of nucleophiles. Because of this behavior, in the present work we describe the microwave synthesis of a series of α-ketoamide and bis-(α-ketoamide) derivatives via the facile ring-opening of N-acylisatin with different amines and di...

The all-alkyl α-tertiary amino acid scaffold represents an important structural feature in many biologically and pharmaceutically relevant molecules. Syntheses of this class molecule, however, often involve multiple steps require activating auxiliary groups on the nitrogen atom or tailored building blocks. Here, we report a straightforward, single-step, modular methodology for synthesis esters....

in this paper the concepts of fuzzifying β − irresolute functions and fuzzifying β − compactspaces are characterized in terms of fuzzifying β − open sets and some of their properties are discussed.