The vir region of Agrobacterium tumefaciens spans at least six transcriptional loci required for crown gall tumorigenesis. The transcriptional induction of two of these vir loci in response to cocultivation with tobacco suspension cells was measured by using bacteria containing mutations in each of the six vir loci located on the Ti plasmid. Induction of these vir genes occurred only in bacteri...

Generic fixed dose combination stavudine (d4T), lamivudine (3TC) and nevirapine (NVP), named GPO-VIR is recommended in the HIV treatment guidelines for Thailand. The long term effectiveness and adverse effects of this drug combination for the treatment of HIV were evaluated in an ambispective study at Bamrasnaradura Infectious Diseases Institute, Nonthaburi Province, Thailand from March 2002 to...

OBJECTIVES To validate a self-expanding transcatheter valve for off-pump transatrial mitral valve-in-ring (VIR) implantation via a left thoracotomy. METHODS Mitral valve annuloplasty was performed via sternotomy during cardiopulmonary bypass on 9 pigs. After successful weaning from extracorporal circulation, the custom-made, self-expanding transcatheter VIR device was deployed under fluorosco...

The gene virilizer (vir) is needed for dosage compensation and sex determination in females and for an unknown vital function in both sexes. In genetic mosaics, XX somatic cells mutant for vir differentiate male structures. One allele, vir2f, is lethal for XX, but not for XY animals. This female-specific lethality can be rescued by constitutive expression of Sxl or by mutations in msl (male-spe...

OPSOMMING Menslike seksualiteit, as ’n psigofisiologiese stelsel, is met reg ’n deel van die arbeidsveld van gesondheidspraktisyns. Dit is egter ’n veld wat agterweë bly weens die sensitiewe aard daarvan. Die verpleegkundige kan ’n belangrike bydrae tot die bevordering van seksuele gesondheid lewer en het daarin ’n opvoedkundige, terapeutiese en breë gemeenskapsrol. Die Gesinsbeplanningsafdelin...

Primêre voorkoming is ’n belangrike terrein vir mediese genetika en die geneticse raadgewer vertolk hierin ’n belangrike roi. Daar is egter spesifieke indikasies vir verwysing van persone na ’n genetiese raadgewer en sy span, ’n Belangrike ontwikkeling in primêre voorkoming van genetiese afwykings is die moontlikheid van voorgeboortediagnose, deur amniosentese, van veral chromosoom afwykings, n...