Micro-slit-beam radiation therapy (MRT) using synchrotron-generated X-ray beams allows for extremely high-dose irradiation. However, the toxicity of MRT in central nervous system (CNS) use is still unknown. To gather baseline toxicological data, we evaluated mortality in normal mice following CNS-targeted MRT. Male C57BL/6 J mice were head-fixed in a stereotaxic frame. Synchrotron X-ray-beam ra...

Autoreactive B lymphocytes that escape central tolerance and mature in the periphery are a liability for developing autoimmunity. IgG insulin autoantibodies that predict type 1 diabetes and complicate insulin therapies indicate that mechanisms for tolerance to insulin are flawed. To examine peripheral tolerance in anti-insulin B cells, we generated C57BL/6 mice that harbor anti-insulin VDJH-125...

The use of dedicated bus shoulders is a key method for implementing bus rapid transit (BRT) in areas that do not have the space for additional infrastructure. However, the narrow width of the bus shoulder and the need to anticipate traffic hazards in the adjacent lane can both be significant stressors for bus drivers. Bus driver mental workload and stress in response to these conditions should ...

ارتقای بازدارندگی دفاعی مستلزم تولید گسترده و متنوع محصولات تجهیزات نظامی است که نیازمند به‌کارگیری ظرفیت‌ها قابلیت‌های وسیع صنعتی است. ازآنجاکه تصدی تملک همه این قابلیت‌ها منطقی اقتصادی نیست، بخشی از فعالیت‌های تولیدی در صنایع دفاعی، برون‌سپاری می­‌شود به ایجاد شبکه بزرگی تأمین‌کنندگان منجر شده گستردگی شبکه، تعاملات همکارانه بهبود عملکرد زنجیره تأمین را یک چالش جدی برای مدیران تبدیل کرده سازما...

A decision support tool for predicting subcutaneous fat depths called BeefSpecs, based on the Davis growth model (DGM), has been developed by the Cooperative Research Centre for Beef Genetic Technologies. Currently, the DGM predicts 12th-rib fat thickness (RFT, mm). To allow predictions of fat thickness at the P8 rump (P8FT, mm) site, the standard carcass fat measurement in the Australian beef ...

The introduction of Bus Rapid Transit (BRT), typically involving the use of exclusive bus lanes and related bus priority measures, is increasingly advocated as a flexible and cost-effective way of improving the attractiveness of public transit in congested urban areas by reducing travel times and variability. These schemes typically involve the reallocation of road space for exclusive use by bu...

BACKGROUND Blue laser imaging (BLI) and linked color imaging (LCI) are the color enhancement features of the LASEREO endoscopic system, which provide a narrow band light observation function and expansion and reduction of the color information, respectively. METHODS We examined 82 patients with early gastric cancer (EGC) diagnosed between April 2014 and August 2015. Five expert and 5 non-expe...

Geometric morphometric shape analyses are used to compare the maxillae of the Kenyanthropus platyops holotype KNM-WT 40000, the Australopithecus deyiremeda holotype BRT-VP-3/1 and other australopiths. The main aim is to explore the relationship between these two specimens and contemporary Australopithecus afarensis Five landmarks placed on lateral views of the maxillae quantify key aspects of t...

Currently, few techniques are available for the evaluation of bacterial biofilm adhesion. These detection tools generally require time for culture and/or arduous handling steps. In this work, the BioFilm Ring Test (BRT), a new technology, was used to estimate the biofilm formation kinetics of 25 strains of Pseudomonas aeruginosa, isolated from the sputum of cystic fibrosis (CF) patients. The pr...