نتایج جستجو برای: ژن bla ctx
تعداد نتایج: 22174 فیلتر نتایج به سال:
BACKGROUND In order to investigate the epidemiology, molecular characteristics, and distribution of extended-spectrum β-lactamase (ESBL)- and AmpC-producing Escherichia coli from community-onset infections in Chinese county hospitals. METHODS E. coli isolates were collected from patients with community-onset infections in 30 county hospitals. ESBL activity was confirmed by double-disc diffusi...
The prevalence of ESBL has been increasing worldwide. In this study, we investigated the molecular characteristics of ESBL among clinical isolates of Escherichia coli from a Japanese tertiary hospital. A total of 71 consecutive and nonduplicate clinical isolates of ESBL-positive E. coli collected at Tohoku University Hospital between January 2008 and March 2011 were studied. The antimicrobial s...
چکیده زمینه و هدف: آنزیم های بتالاکتامازی ، مهمترین عامل مقاومت به آنتی بیوتیکهای خانواده بتالاکتام در میان باکتری های گرم منفی می باشد. امروزه شاهد افزایشروز افزون عفونتهای ناشی از آن ها در جهان هستیم و این یکی از مشکلات بهداشتی درمانی نو ظهور در سطح دنیا ست. هدفاز این تحقیق بررسی الگوی حساسیت آنتی بیوتیکی نسبت به آنتی بیوتیک های بتالاکتام و تحقیق پیرامون وجود ژن می باشد. e.coli در نمونه های ا...
BACKGROUND Extended spectrum β-lactamases (ESBLs), a group of enzymes conferring resistance to third generation cephalosporins have rapidly increased in Enterobacteriacae and pose a major challenge to human health care. Resistant isolates are common in domestic animals and clinical settings, but prevalence and genotype distribution varies on a geographical scale. Although ESBL genes are frequen...
Among 120 Escherichia coli isolates from Thai patients, 37 and 9 isolates were extended-spectrum beta-lactamase (ESBL) and suspected ESBL producers respectively while 5 E. coli isolates from 120 Thai healthy adults were suspected ESBL producers. Integrase (intl1) gene was detected in 99% of the clinical and 87% of the non-clinical isolates. Among 37 ESBL producers, percent recovery of bla(TEM),...
background: resistance to contemporary broad-spectrum b-lactam antibiotics mediated by extended-spectrum b-lactamases (esbls) is increasing worldwide. klebsiella pneumoniae , an important cause of nosocomial and community acquired urinary tract infections has rapidly become the most common esbl producing organism. we examined esbl production in urinary isolates of k. pneumoniae in relation to t...
There is a global increase in infections caused by Enterobacteriaceae with plasmid-borne β-lactamases that confer resistance to third-generation cephalosporins. The epidemiology of these bacteria is not well understood, and was, therefore, investigated in a selection of 636 clinical Enterobacteriaceae with a minimal inhibitory concentration >1 mg/L for ceftazidime/ceftriaxone from a national su...
background : the emergence and increase in the incidence of extended-spectrum beta lactamase (esbl) producing escherichia coli has become an emerging challenge especially in hospitalized patients with uti. the aim of the present study was to survey the frequency of bla ctx-m genotype in esbl producing e. coli isolated from hospitalized patients with uti and determination of their antibiotic res...
سابقه و هدف: آنزیمهای بتالاکتامازهای طیف گسترده، هیدرولیز کننده پنیسلینها و سفالوسپورینها میباشند. هدف از این بررسی تعیین فراوانی سویههای اشریشیاکلی تولیدکننده ژنهای بتالاکتامازهای CTX-M،TEM،SHV با روش Multiplex PCR و ارتباط آنها با ایجاد مقاومت آنتی بیوتیکی در سویههای اشریشیاکلیاست. مواد و روشها: در این مطالعه مقطعی، تعداد 55 سویه اشریشیاکلی با استفاده از محیط کشت EMB آگار و کروم آگا...
We applied in vitro evolution to an Escherichia coli strain containing bla(CTX-M-2) and obtained 10 independent mutant bla(CTX-M-2) alleles that confer elevated resistance to ceftazidime (MIC > or = 32 microg/ml) but lost the ability to confer resistance to cefepime. All alleles had a Pro-to-Ser substitution at position 167.
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