Hgs/Hrs is a tyrosine-phosphorylated FYVE finger protein that is induced by stimulation with various cytokines and growth factors. Here we show that Hgs plays critical roles in the signaling pathway for the interleukin-2-induced activation of the serum-response element and cyclic AMP-response element of the c-fos promoter. We found that Hgs associated physically with transforming growth factor-...

  Background: Heavy exercise cause muscle damage associated with production of inflammatory agents. The purpose of present study was to determine the effect of acute and 14-day Coenzyme Q10 supplementation on inflammatory, blood lactate and muscle damage in male middle-distance runners.   Methods : Eighteen male middle-distance runners in a randomized and quasi experimental study were allocated...

background hearing loss is the most common congenital disorder the incidence of which is further increased in the presence of risk factors for hearing loss among newborns admitted to the neonatal intensive care unit (nicu). the aim of this study was early diagnosis and intervention for hearing loss in newborns discharged from nicu. materials and methods this prospective cohort study was conduct...

purpose : to investigate the correlation between corneal biomechanical properties and tomographic parameters of pentacam methods : corneal biomechanical properties and tomographic results of 36 normal subjects were measured by ocular response analyzer (ora) and pentacam and the correlation between these two measurements were analyzed with pearson correlation test with spss version16. results : ...

background: the present study deals with the effect of helminthic infection as nematode parasite like aspiculuris tetraptera on the haematological parameters of infected and vaccinated mice. methods: totally 15 mice were used. five mice were used for positive control, 5 mice used for nega­tive control and 5 mice used for experiment. the hematological parameters were studied viz. rbc, hb, and se...