Background: Infertility problem affects young couples. One of the known causes of spermatogenic disorder is chemotherapy in patients with cancer. Since dividing cells are mainly affected by anticancer drugs, the aim of the present study is to investigate the preventive effect of GnRH antagonist on spermatogenic defect produced by anticancer drug. Materials and Methods: In the present study 30 a...

the objective of this research was to evaluate the cause of fertility reduction after chemotherapy.cyclophosphamide is a common chemotherapy and immunosuppressive agent used for the treatment of awide range of neoplastic and some auto-immune diseases. in the present study, morphometrical changes inthe ovary and uterus of 12 5–6-week-old female syrian mice after intraperitoneal injection of 75 m...

abstract arsenic (as) contamination of soils is a global problem. legumes are often used in remediation of contaminated sites because of their capacity to fix nitrogen. in the present study, the effects of inoculation of bean (by rhizobium leguminosarum bv. phaseoli) on plant uptake and tolerance to arsenic were investigated. an experiment with a factorial arrangement, two levels of inoculation...

background: exposure to arsenic is associated with impairment of male reproductive function by inducing oxidative stress. silymarin with an antioxidant property scavenges free radicals. objective: the aim of this study was to investigate if silymarin can prevent the adverse effects of sodium arsenite on ram sperm plasma membrane and acrosome integrity. materials and methods: ram epidydimal sper...

objective(s): angiotensin ⅱ type 1 receptor blockers (arbs) represent one of the widely used antihypertensive agents. in addition to anti-hypertension effect, some arbs also show other molecular effects such as activating peroxisome proliferator-activated receptor-γ and so on. here we studied the effects of telmisartan on the rat isolated mesenteric artery rings pre-contracted by phenylephrine ...

background: ketamine is a commonly used intravenous anesthetic which produces dissociation anesthesia, analgesia, and amnesia. the mechanism of ketamine-induced synaptic inhibition in high-level cortical areas is still unknown. we aimed to elucidate the effects of different concentrations of ketamine on the glutamatergic synaptic transmission of the neurons in the primary somatosensory cortex b...

To further clarify the specific photochemical mechanisms of salicylic acid (SA)-mediated adaptation to salt stress, this experiment was conducted to examine the effect of SA (100 and 500 μM) on photosynthesis, antioxidative capacity and phenolic metabolism in strawberry plants under salt stress (50 mM). The results showe...

background: the aim of this study was to compare the effects of conventional acid etching and laser etching on the nano-mechanical properties of the dental enamel using nano-indentation test. materials and methods: in this experimental in vitro study, buccal surfaces of 10 premolars were divided into three regions. one of the regions was etched with 37% phosphoric acid and another etched with e...

A search for periodic gravitational-wave signals from isolated neutron stars in the NAUTILUS detector data is presented. We have analyzed half a year of data over the frequency band 〈922.2; 923.2〉Hz, the spindown range 〈−1.463 × 10−8; 0〉 Hz/s and over the entire sky. We have divided the data into two day stretches and we have analyzed each stretch coherently using matched filtering. We have imp...