Cadmium (Cd) is a highly toxic heavy metal, wide occupational and an environmental pollutant, affecting human health. Probiotics especially lactic acid bacteria (LAB) have the capacity to bind, remove and to decrease tissue cadmium levels. The objective was to evaluate the potency of Cd binding capacity, antioxidative properties of probiotic bacteria against cadmium in vitro and its probable de...

Objectives: The natural origin of medicinal plants does not guaranteed their safety, as there are no sufficient studies on the safety, efficacy and toxicity to support their beneficial claims. Hence, this study aimed at investigating the oral acute toxicity of Adansonia digitata L. fruit shell extract on mice. Methods: Maceration method was employed for the extraction of Adansonia digitata fru...

Toxicity testing is conducted to determine the potential human health hazards of chemicals and products. Acute systemic toxicity testing is used to properly classify and appropriately label materials with regard to their lethality potential in accordance with established regulatory requirements (49 CFR 173; 16 CFR 1500; 29 CFR 1910; 40 CFR 156). Non-lethal parameters may also be evaluated in ac...

The article is devoted to the study of acute toxicity drug «Zidovudine»

Background: Exposure to any xenobiotic can disturb the metabolic activities of particular organs. Hence present study is designed to find changes in hepatic biochemistry, histochemistry and histopathology besides serum enzyme levels after acute and sub-acute treatment with mercuric chloride, a heavy metallic compound, in albino rat (Rattus norvegicus). Materials & methods: Thirty albino rat...

the isocyanates are widely used as precursors of polyurethane products, as well as carbamate insecticides. toluene 2,4-diisocyanate (tdi) is one of the most important commercially used isocyanates. humans may be exposed to tdi by inhalation, ingestion, dermal and eye contact. tdi is a powerful irritant to the mucosal membranes of the gastrointestinal and respiratory tracts, eyes and the skin. p...

background: rhabdomyolysis is one of the major complications of poisoning caused by alcohol, narcotics, and psychotropic substances acute toxicity, which might lead to acute renal failure and even death. this study aimed to evaluate clinical and laboratory findings of rhabdomyolysis syndrome in poisoning patients who were admitted to poisoning ward of farshchian hospital of hamadan, iran. metho...