In covering wounds, efforts should include utilization of the safest and least invasive methods with goals of achieving optimal functional and cosmetic outcome. The recent development of advanced wound healing technology has triggered the use of cells to improve wound healing conditions. The purpose of this review is to provide information on clinically available cell-based treatment options fo...

Wound repair and regeneration is a highly complex combination of matrix destruction and reorganization. While major hurdles remain, advances over the past generation have improved the clinician's armamentarium in the medical and surgical management of this problem. The purpose of this manuscript is to review the current literature regarding the pragmatic use of three of the most commonly employ...

INTRODUCTION Conceptual inspiration from nature is not new, and many engineering approaches can be considered to have been inspired by observing natural systems. The healing potential and repair strategies of living organisms is increasingly of interest to designers seeking lower mass structures with increased service life who wish to progress from a conventional damage tolerance philosophy. Na...

OBJECTIVE The treatment of patients with cancer has advanced into a complex, multimodal approach incorporating surgery, radiation, and chemotherapy. Managing wounds in this population is complicated by tumor biology, the patient's disease state, and additional comorbidities, some of which may be iatrogenic. Radiation therapy, frequently employed for local-regional control of disease following s...

OBJECTIVES To evaluate the influence of shock wave therapy (SWT) on radiographic evidence of bone healing after tibial plateau leveling osteotomy (TPLO). METHODS Healthy dogs between two to nine years of age that underwent TPLO were randomly assigned to receive either electro-hydraulic SWT (1,000 shocks) or sham treatment (SHAM). Treatment or SHAM was administered to the osteotomy site immedi...

Skin regeneration requires the coordinated integration of concomitant biological and molecular events in the extracellular wound environment during overlapping phases of inflammation, proliferation, and matrix remodeling. This process is highly efficient during normal wound healing. However, chronic wounds fail to progress through the ordered and reparative wound healing process and are unable ...

Wound management is to provide an appropriate environment for the wound its healing without breakdown of skin. It ongoing treatment process that includes size, severity, depth, and location wound. Carbon-based nanomaterials have greater potential chronic infections as compared conventional approaches. The physiochemical properties these nanostructured materials may enable clinicians develop mor...

This study examined the adverse events associated with advanced laryngeal cancer treatment in International Medical Center Saitama University and described countermeasures taken. During chemoradiotherapy, special attention should be paid to patients prevent need for discontinuation of CDDP due renal dysfunction. Regarding surgical cases, cases minor leak were relieved by conservative treatment,...