An imaging-based computational framework for simulation of airflow in subject specific breathing human lungs is established. The three-dimensional (3D) airways of up to 9 generations and lobes are segmented and reconstructed from computed tomography (CT) images. Beyond the CT-resolved 3D airways, a volume filling method is applied to generate the one-dimensional (1D) conducting airway tree that...

lumen endotracheal tube or bronchial blocker with general anesthesia is the first anesthetic choice in thoracic surgery. However, general anesthesia with mechanical ventilation carries a risk of side-effects related to tracheal intubation and general anesthesia, such as airway complications, ventilation-induced lung injury, and residual neuromuscular blockade [1-3]. Thanks to advances in minima...

BACKGROUND There is strong evidence that malocclusion and body posture are interdependent. The relationship between improvement of nasopharyngeal airway, correction of malocclusion by orthodontic treatment or orthognathic surgery, and changes in body posture were evaluated in several studies. The purpose of the present study was to analyze the effect of the orthodontic treatment with Twin-block...

We assessed the changes in regional lung function following instillation of surfactant in a model of respiratory distress syndrome (RDS) induced by whole lung lavage and mechanical ventilation in eight anaesthetized, paralyzed, and mechanically ventilated New Zealand White rabbits. Regional specific ventilation (sV̇) was measured by K-edge subtraction synchrotron computed tomography during xenon...

A novel algorithm is presented that links local structural variables (regional ventilation and deforming central airways) to global function (total lung volume) in the lung over three imaged lung volumes, to derive a breathing lung model for computational fluid dynamics simulation. The algorithm constitutes the core of an integrative, image-based computational framework for subject-specific sim...

Correction to: Local block and Awake Intubation in a Patient with Laryngeal Mass and Anticipated Difficult Airway: A Case Report       Hooshang Akbari1, Ravanbakhsh Esmaeili2   1 Assistant Professor, Department of Anesthesiology, Faculty of Paramedical, Mazandaran University of Medical Sciences, Sari, Iran 2 Assistant Professor, Department of Medical Surgical Nursing...

Most contemporary oculoplastic surgery is performed under local anesthesia (1). The move away from general anesthesia has proved both efficient and cost effective, as all but the more major eyelid surgery can now be performed as a day-case pro c e d u re. Local anesthesia also has the advantage of allowing patient cooperation during surgery, which can aid in the prediction of postoperative outc...