نتایج جستجو برای: allergenicity

تعداد نتایج: 1018  

2017
Yepei Zhu Wei Wang Tianhao Chen Guanghong Zhou

The objective of this study is to investigate the impact of Ultra-High Pressure (UHP) combined with moderate heat treatment on the allergenic properties of Bovine Serum Albumin (BSA). The effects of high pressure treatment at 100-500 MPa on allergenicity and structural properties of BSA were investigated. This study was performed using Competitive Indirect-Enzyme Linked Immunosorbent Analysis (...

2016
Andrea Obersteiner Stefanie Gilles Ulrike Frank Isabelle Beck Franziska Häring Dietrich Ernst Michael Rothballer Anton Hartmann Claudia Traidl-Hoffmann Michael Schmid Ulrich Melcher

Pollen allergies have been rapidly increasing over the last decades. Many allergenic proteins and non-allergenic adjuvant compounds of pollen are involved in the plant defense against environmental or microbial stress. The first aim of this study was to analyze and compare the colonizing microbes on allergenic pollen. The second aim was to investigate detectable correlations between pollen micr...

Journal: :Molecular nutrition & food research 2011
Fany Blanc Yvonne M Vissers Karine Adel-Patient Neil M Rigby Alan R Mackie A Patrick Gunning Nikolaus K Wellner Per S Skov Laetitia Przybylski-Nicaise Barbara Ballmer-Weber Laurian Zuidmeer-Jongejan Zsolt Szépfalusi Janneke Ruinemans-Koerts Ad P H Jansen Hervé Bernard Jean-Michel Wal Huub F J Savelkoul Harry J Wichers E N Clare Mills

SCOPE Roasting rather than boiling and Maillard modifications may modulate peanut allergenicity. We investigated how these factors affect the allergenic properties of a major peanut allergen, Ara h 1. METHODS AND RESULTS Ara h 1 was purified from either raw (N-Ara h 1) or roasted (R-Ara h 1) peanuts. Boiling (100°C 15 min; H-Ara h 1) resulted in a partial loss of Ara h 1 secondary structure a...

Journal: :Iranian journal of allergy, asthma, and immunology 2014
Cui-cui Duan Ai-li Li Li-jie Yang Rui Zhao Wen-guang Fan Gui-cheng Huo

Cow's milk allergy is one of the most common food allergies in childhood. Beta-lactoglobulin (β- lg) is a dominant allergen in cow's milk. Hydrolysis is known as an effective method to reduce the allergenicity of proteins. Thus, the objective of this study was to compare the allergenicity of β-lg and its hydrolysates using an animal model. Twenty four BALB/c mice were divided into three groups ...

Journal: :International archives of allergy and immunology 2015
Sitaram Parvataneni Babu Gonipeta Harini G Acharya Venu Gangur

BACKGROUND Shellfish (SF) allergy is a leading cause of systemic anaphylaxis in humans. An adjuvant-free mouse model to evaluate allergenicity and oral anaphylaxis to SF is currently unavailable. Here, we tested the hypothesis that transdermal exposure (TDE) to SF protein extract (SFPE) not only elicits a systemic allergic immune response but also will clinically sensitize mice for oral anaphyl...

Journal: :Annals of allergy, asthma & immunology : official publication of the American College of Allergy, Asthma, & Immunology 2003
Ricki M Helm

BACKGROUND Food biotechnology represents advancement in the traditional interspecies and intergeneric breeding methods for improving food supplies worldwide. With respect to safety, foods developed through biotechnology techniques represent one of the most extensively reviewed agricultural advancements in history. OBJECTIVE To review the relevant issues with respect to foods from genetically ...

2000
M. WIGOTZKI Michael Wigotzki Angelika Paschke

The allergenicity of hazelnuts treated with different proteolytic enzymes was examined and compared by SDS-PAGE / immunoblotting and EASTinhibition experiments using sera of 16 hazelnut allergic individuals. 30 min treatment with the enzymes protease, elastase and trypsin eliminated the allergenicity of the hazelnut proteins, which can be shown by means of immunoblotting experiments. EASTinhibi...

Journal: :Regulatory toxicology and pharmacology : RTP 2016
Kitty Verhoeckx Henrike Broekman André Knulst Geert Houben

To solve the future food insecurity problem, alternative and sustainable protein sources (e.g. insects, rapeseed, fava bean and algae) are now being explored for the production of food and feed. To approve these novel protein sources for future food a comprehensive risk assessment is needed according to the European food legislation. Allergenicity risk assessment might pose some major difficult...

Journal: :Allergologia et immunopathologia 2013
R I Kosti M Triga S Tsabouri K N Priftis

Food allergy can be considered a failure in the induction of oral tolerance. Recently, great interest has been focused on understanding the mechanisms and the contributing factors of oral tolerance development, hoping for new definitive interventions in the prevention and treatment of food allergy. Given that food processing may modify the properties and the nature of dietary proteins, several ...

Journal: :iranian journal of allergy, asthma and immunology 0
cui-cui duan key laboratory of dairy science, ministry of education, northeast agricultural university, harbin 150030, china ai-li li key laboratory of dairy science, ministry of education, northeast agricultural university, harbin 150030, china li-jie yang key laboratory of dairy science, ministry of education, northeast agricultural university, harbin 150030, china rui zhao key laboratory of dairy science, ministry of education, northeast agricultural university, harbin 150030, china wen-guang fan key laboratory of dairy science, ministry of education, northeast agricultural university, harbin 150030, china gui-cheng huo key laboratory of dairy science, ministry of education, northeast agricultural university, harbin 150030, china

cow’s milk allergy is one of the most common food allergies in childhood. beta- lactoglobulin (β-  lg) is  a dominant  allergen in  cow’s milk. hydrolysis is  known as  an effective method to reduce the allergenicity of proteins. thus, the objective of this study was to compare the allergenicity of β-lg and its hydrolysates using an animal model. twenty four balb/c mice were divided into three ...

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