BACKGROUND We assessed the suitability of event-related potential frontal and temporoparietal P300 changes as intermediate phenotypes in genetic studies of schizophrenia. We applied a principal component analysis approach based on the notion that P300 abnormalities in siblings of schizophrenic patients may involve a widespread network of relatively weak cortical generators and because an earlie...

UNLABELLED We reviewed 24-h electrocardiographic recordings from 214 genotyped subjects--97 with long-QT syndrome type 1 (LQT1), 62 with LQT2, and 55 unaffected--to record maximal diurnal amplitude ratios between late and early T-wave peaks. Maximal amplitude ratios between late and early T-wave peaks were higher in symptomatic than in asymptomatic patients both in LQT1 (3.2 +/- 1.0 vs. 2.3 +/-...

Monte Carlo (MC) simulations and series expansion (SE) data for the energy, specific heat, magnetization and susceptibility of the 3-state Potts model on the square lattice are analyzed in the vicinity of the critical point in order to estimate universal combinations of critical amplitudes. We estimate these amplitudes using the correction-to-scaling exponents predicted by conformal field theor...

OBJECTIVE 1) To determine if unexplained ear fullness might be a symptom of endolymphatic hydrops (EH) by using Electrocochleography (ECochG) SP/AP area and amplitude ratios. 2) To assess if individuals with unexplained ear fullness without vertigo differ significantly from individuals with ear fullness due to Ménière's disease (MD). MATERIALS AND METHODS In a case-control study in our tertia...

Soil sites have a profound effect on ground motion during earthquakes due to their low wave speeds, layered structure, and nonlinear constitutive relationship. Measurements of nonlinear soil response under natural conditions are critical to understanding soil behavior during earthquakes. Currently, quantitative measurements of nonlinear soil response are derived from laboratory experiments on s...

in many signal processing applications, an appropriate measure to comparetwo signals plays a fundamental role in both implementing the algorithm andevaluating its performance. several techniques have been introduced in literature assimilarity measures. however, the existing measures are often either impractical forsome applications or they have unsatisfactory results in some other applications....

BACKGROUND Electrocochleography (ECochG) is useful in supporting the diagnosis of Meniere disease (MD). Possible MD (early disease as defined by the 1995 American Academy of Otolaryngology-Head and Neck Surgery Committee on Hearing and Equilibrium) is a readily treatable form of MD. OBJECTIVES To identify whether ECochG summating potential/action potential (SP/AP) area curve measures are more...