Objective- Bone regeneration is a multifactorial phenomenon which contributed to several factors. It is reported that risedronate is effective for musculoskeletal diseases. The current study was to determine effectiveness of the risedronate-loaded nano capsules for calvaria healing in rabbit.Design- Experimental study.Procedures- 15 white adult male New Zealand rabbits were used. Fo...

Introduction: Diagnosis of lesions and bone defects is very important and there is a lack of substantial studies on the most appropriate method for bone defect measurement. Hence, the aim of this study is to evaluate the accuracy of multi-slice computed tomography (MSCT) and cone-beam computed tomography (CBCT) in the diagnosis of mandibular bone defects present in sheep. Material & Methods: T...

background: in several conditions we have face cranial bone defects. reconstruction of these defects remains one of the most challenging problems encountered by craniofacial surgeons.   objective: to evaluate bone repair in cranial bone defects by use of an implant made of octacalcium phosphate in combination with bone matrix gelatin (ocp/bmg).   methods: we used 40, 5–6-week-old male sprague-d...

backgroundcongenital generalized lipodystrophy (cgl) is a rare disease. it is associated with near total fat loss, severe insulin resistance and hypoleptinemia leading to metabolic derangements.case presentationwe report a 25- year- old female with 1-acylglycerol-3-phosphate-o-acyltransferase 2 (apgat2) mutation, and both sclerotic and lytic bone lesions together for the first time. bone cyst i...

leukemia is the most common childhood cancer and accounts for 30-40% of all malignancies. a retrospective review  was performed of the hospital records of 9 children, 6 boys and 3 girls, aged  from 2.5 to 15 years with all initially referred to nemazee hospital nuclear medicine center for whole body bone scanning between 2000 and 2002. bone marrow pathology established all (l1) in two and all (...

background: th e eff ects of chronic valproic acid administration on bone health have been a matter of concern and controversy.in this study, the bone status following valproate intake was assessed by using several bone-related biochemical markers. materials and methods: in this case-control study, 62 epileptic patients and 40 age- and gender-matched controls were enrolled. the patients had bee...

This study was undertaken to assess the frequency of decreased bone mineral density and its risk factors as well as its impact on the quality of life during childhood among hemophiliac patients. Materials and Methods: Thirty seven children with severe hemophilia A and B, referred to Mofid Children’s Hospital during 2010, were selected. For all patients the joint score, body mass indexes, bone...