Andrographis paniculata (Nees), is a valuable traditional medicinal plant and it has many important bioactive compounds. It cures and prevents a number of diseases in human beings. It is a boon of the nature of human healthy life. It cures cold, fever, colic pain, active against inflammatory, antidiabetic activity, antioxidant, antifertility, cardiovascular and anti-virus including inhibited HI...

Major drawbacks of chemotherapeutic agents are their toxic side effects and lack of tumor specificity. Immunological and biochemical studies were here carried out to investigate protective effects of ethanolic extract of Andrographis paniculata against cyclophosphamide (CTX) induced toxicity in vivo. Intraperitoneal administration of the extract significantly increased the total WBC account (32...

Andrographis paniculata (Burm.f.) Nees is a medicinal herb in the family Acanthaceae. The leaves of the mature plant contain abundant diterpinoids of medicinal properties.The objectives of the present study were to investigate the impacts of compost tea rates on photosynthesis parameters and antioxidant reactions of A. paniculata. The plant was propagated using seed and planting in a polybag. A...

Antimicrobial properties and medicinal effects of Andrographis paniculata was carried out in this study. leaves were collected from Federal Polytechnic Nekede, Owerri identified by a botanist. The clinical isolates Klebsiella specie, Vibrio cholera Escherichia coli obtained the Microbiology Department Medical Centre, Owerri, then sub-cultured on sterile Nutrient agar microbial culture diluted w...

Objective: The present investigation addresses the inhibitory potential of five Andrographis paniculata (AP) extracts of different polarity and its three active constituents on UGT1A1, UGT1A4 and UGT2B7. Methods: Bioluminescent assay with luciferin as a substrate was used to determine IC50 values for all extracts and constituents. The kinetic enzyme inhibition experiments were subsequently perf...