background: the aim of this study was to determine the prevalence and viral load of epstein–barr virus (ebv) and human herpesvirus‑6 (hhv‑6) in different histopathologic grades of oral squamous cell carcinoma (oscc). methods: forty‑five formalin‑fixed paraffin‑embedded tissue section of oscc patients were analyzed by quantitative real‑time polymerase chain reaction for detection of ebv and hhv‑...

Skewing of the T-cell receptor repertoire of CD8(+) T cells has been shown in some persistent infections with viruses, such as human immunodeficiency virus, simian immunodeficiency virus, and Epstein-Barr virus. We have demonstrated that similar distortions also occur in nonpersistent measles virus infection. In addition, two of four children immunized with live, attenuated measles virus showed...

Background: Gastric cancer is a leading cause of death worldwide and the average survival rate of patients within a year of diagnosis remains low. Currently, surgical resection is the major treatment strategy, and the effectiveness of chemotherapy remains debatable. Infections involving Helicobacter pylori (H. pylori) and the Epstein-Barr virus have been implicated in gastric cancer pathogenesi...

background: among the eight known human herpes viruses, epstein- barr virus (ebv) is considered to be sexually transmissible. this study was conducted to evaluate the seroepidemiology of this infection in married and unmarried iranian couples. methods: in this comparative observational and cross-sectional study, 160 men and women were divided into married and unmarried groups. serum igg and igm...

opportunistic infections are the leading cause of hospitalization and morbidity in human immunodeficiency virus (hiv) positive patients and are the most common cause of death between them. we aimed to measure igg antibody against ebv viral capsid antigen (ebv-vca igg) to determine the seroprevalence of this infection in hiv-positive population. a case-control study between september 2011 and oc...

introduction: quantification of epstein - barr virus (ebv) in peripheral blood mononuclear cells (pbmnc) of allogenic bone marrow transplant (bmt) recipients is important because ebv-associated posttransplant lymphoproliferative disease (ptld) can occur after transplantation due to immunosup-pression therapy. methods: to this end we chose real-time pcr using taqman probe. for the standard curve...

conclusions considering the results, accurate and on time diagnosis of ebv primary infection in both children and adolescents will help prevent unnecessary hospitalization, medication and incorrect medical decisions. in addition, this will decrease further treatment costs and related medical procedures. background many children become infected with epstein-barr virus (ebv) during their childhoo...

The acyclic nucleoside phosphonates HPMPC (cidofovir), PMEA (adefovir), and PMPA (tenofovir) have proved to be effective in vitro (cell culture systems) and in vivo (animal models and clinical studies) against a wide variety of DNA virus and retrovirus infections: cidofovir against herpesvirus (herpes simplex virus types 1 and 2 varicella-zoster virus, cytomegalovirus [CMV], Epstein-Barr virus,...