background multiple sclerosis (ms) is a demyelinating condition affecting the central nervous system. although the cause of this condition is unknown, patients with ms seem to have genetic vulnerability to certain environmental factors such as infection that could trigger this condition. objectives we conducted this study to determine whether ms risk increases following primary infection with e...

background: expression of epstein-barr virus latent member protein-1 (ebv lmp-1) and loss of p16 protein expression are documented in lymphoma, indicating a relationship between them, but this relationship is not clear and sometimes contradictory. thus, this study was conducted to examine the relationship between the loss of p16 and ebv lmp-1 expression in jordanian patients diagnosed with lymp...

how to cite this article: hashemian s, ashrafzadeh f, akhondian j, beiraghi toosi m. epstein-barr virus encephalitis: a case report. iran j child neurol. 2015 winter;9(1):107-110.     abstract many neurologic manifestations of epstein-barr virus (ebv) infection have been documented, including encephalitis, aseptic meningitis, transverse myelitis, and guillain-barre syndrome. these manifestation...

objectives: regarding the implication of viruses particularly herpes in pemphigus vulgaris, we sought to assess and compare the level of immunoglobulin g (igg) antibodies against herpes simplex virus types 1 and 2 (hsv1 and hsv2), cytomegalovirus (cmv) and epstein-barr virus (ebv) in patients with pemphigus vulgaris and healthy people.     materials and methods: in this cross-sectional study, 2...

Background: Scleroderma is a chronic systemic disorder that affects the connective tissues. It is characterized by several immune manifestations, inflammation, vascular damage, and fibrosis. Some of the viral infections with complex mechanisms are involved in the development and progression of many autoimmune diseases, such as scleroderma. The present study aimed to investigate the serological ...

results there was a significant difference in prevalence of ebv presence between patients and controls. the ebv was found by rt-pcr in 19 (63.33%) out of 30 patients and only in eight (26.7%) of 30 control samples. the p = 0.004, was calculated using chi-square test (or: 4.75; 95% ci: 1.58 ‒ 14.25). conclusions our study is the first investigation performed on patients with lch and its possible...

INTRODUCTION: Epstein-Barr virus (EBV) and cytomegalovirus (CMV) are herpesviruses, which account for the majority of oral viral infections. Herpes simplex virus, varicellazoster virus, and Epstein-Barr virus infections nearly always result from reactivation of latent virus, while cytomegalovirus infections, besides presenting as reactivated disease, are almost as likely to present as a primary...

background and objectives: epstein barr virus (ebv) is one of the members of herpesviridae family and a sub-category of gamma herpes virinae. ebv, which normally has cr2 or cd21 receptors on b-lymphocytes, has mutagenic features for them. the virus plays an important role in causing some malignant cancers. about 30% of the cases with non-hodgkin’s lymphoma are diffuse large b-cell lymphoma (dlb...

background epstein barr virus (ebv) is one of the most common viral infections in human population. ebv has a significant role in pathogenesis of hodgkin's lymphoma, burkitt's lymphoma and nasopharyngeal carcinoma. the role of ebv in non-hodgkin’s lymphoma, diffuse large b cell (nhl - dlbl) in the head and neck is controversial. objectives the purpose of this study is to find out the ...

Epstein-Barr viral capsid antigen and nuclear antigen produced by modified procedures were evaluated for use in measuring viral capsid antigen immunoglobulin M and Epstein-Barr virus nuclear antigen antibody responses in sera from patients with suspected Epstein-Barr virus infections. Viral capsid antigen production was stimulated with a phorbol ester, and the Epstein-Barr virus nuclear antigen...