BACKGROUND/AIMS The oxidation of xenobiotic-derived aromatic aldehydes with freshly prepared liver slices has not been previously reported. The present investigation compares the relative contribution of aldehyde oxidase, xanthine oxidase and aldehyde dehydrogenase activities in the oxidation of vanillin, isovanillin and protocatechuic aldehyde with freshly prepared liver slices. METHODS Vani...

A lag phase in the spectrophotometric assay progress curve of aldehyde oxidation by HL-ADH was observed and characterised. The aldehyde oxidation and aldehyde dismutation reactions were shown to be related, and a mechanism to explain net aldehyde oxidation was proposed. The spectrophotometric assay was shown to be unsuitable for measurement of kinetic parameters for aldehyde oxidation by HL-ADH...

We have investigated the Kodak Ektachem 400 Analyzer procedure for CO2 for interferences from benzyl alcohol, benzoic acid, and several compounds structurally similar to benzoic acid. Benzoic acid in plasma, at concentrations found in neonates intoxicated with benzyl alcohol, caused a large increase in the results for CO2, as did substantially above-normal concentrations of certain fatty acids ...

Bacterial luciferase catalyzes the reaction of FMNH2, O2, and an aliphatic aldehyde to yield the carboxylic acid, FMN, water and blue-green light. The kinetics of the bacterial luciferase reaction were measured by stopped-flow spectrophotometry at pH 7 and 25 degrees C for the series of aldehydes from n-heptanal to n-undecanal. The rate of formation of the 4a-hydroperoxyflavin intermediate was ...

The 2,4- and 2,5-dihydroxybenzamides (8, 9) were synthesized from their corresponding methyl esters. The structures and the spectral properties of investigated salicylic acid (1), 2,4- and 2,5-dihydroxy benzoic acids (2, 3), their methyl esters (4-6) and amides (7-9) were analyzed by means of FT-IR and one- and two-dimensional homo- and heteronuclear 1H and 13C NMR spectroscopies. Comparison of...

cr(iii), co(ii), ni(ii), cu(ii) and zn(ii) salts of 2-(4-nitrophenylaminocarbonyl)benzoic acid were characterized by physical, analytical and spectroscopic studies and checked for their  in-vitro antimicrobial activity against three bacterial strains, mycobacterium smegmatis (gram +ve), escherichia coli (gram -ve), pseudomonas aeuroginosa (gram -ve) and three fungal strains, nigrospora oryzae, ...

In the present study, p-amino phenol (PAP) and p-amino benzoic acid (PABA) have been modified as lipids palmitoyl p-amino phenol (PPAP) and palmitoyl N p-amino benzoic acid (N-PPABA) by a simple amide formation reaction of the respective compounds with palmitoyl chloride. On screening PPAP and N-PPABA for pharmacological activity, PPAP (an analogue of paracetamol) has been found to exhibit pote...

the catalytic oxidation of toluene to benzoic acid in the liquid phase has been studied in an un-stirred tank reactor. low concentration of acetic acid was added in order to increase the solubility of the catalyst in toluene. the dependence of the rate of reaction on the concentration of toluene catalyst and oxygen pressure was studied. it has been suggested that liquid phase oxidation of tolue...

Aldehyde assisted fractionation of biomass produces an acetal-stabilised lignin that is fully upgradeable. We exploit the aldehyde to control lignin's physical properties, producing lignins can be soluble in both polar and apolar solvents.