objective: vitiligo is a rare side effect of carbamazepine whose exact mechanism is unknown. the aim of this report is to describe a single case of vitiligo induced by carbamazepine . methods: the case was a patient with bipolar i disorder whose medications were changed from valproate to carbamazepine and who developed vitiligo after a short while. we followed the case for about four years when...

Many patients within the Bipolar spectrum, especially when recurrence is high and the inter-episodic period is not free of affective manifestations, may meet criteria for personality disorders. This is particularly true for cyclothymic patients, who are often misclassified as borderline personality disorder because of their extreme mood instability and reactivity. In patients with cyclothymic t...

OBJECTIVES The aims of the study were to validate the Turkish version of the Mood Disorder Questionnaire (MDQ) as a screening tool and to determine its optimum cut-off value for bipolar disorder. METHODS Validation of the Turkish version of the MDQ was conducted on a sample of 309 consecutive patients who attended the psychiatry outpatient unit of 2 different university hospitals. The Structu...

Inborn errors of metabolism represent rare but important causes of psychiatric disorders in adolescents or adults. Here we describe a young male presenting with symptoms of bipolar affective disorder with underlying metabolic disorder. During hospitalization he was noticed to have increased sensitivity to antipsychotics, lithium and had poor response to treatment. He was detected to have metabo...

Some of the most challenging facets of bipolar disorder involve the management of its depressive symptoms. This article will focus on the pharmacologic management of this phase of bipolar disorder, describing the evidence base for controlled studies, emerging treatments, and expert recommendations. An unmet need exists for acute and maintenance treatments that target depressive symptoms in bipo...

Background: Bipolar mood disorder type 1 is one of the most serious psychiatric disorders. We aimed to assess the efficacy of a short-term family–focused treatment for patients with bipolar mood disorder type 1 in a one-year follow-up period. Methods: Sixty patients with bipolar mood disorder and acute mania episodes who referred to Ibn-e-Sina Psychiatric Hospital in Mashhad were recruited. Hal...

BACKGROUND bipolar disorder is frequently misdiagnosed or diagnosed late. Misdiagnosis of Bipolar Disorder can have serious implications for prognosis and treatment of this condition. METHOD patients in a Community Mental Health Team were systematically screened for Bipolar Disorder. RESULTS There was a substantial increase in the number of bipolar patients diagnosed in the Community Mental...

bipolar spectrum disorders may often go undiagnosed or unrecognized. the aim of this study was to determine the proportion of bipolar disorder symptoms in iranian patients with a major depressive episode.313 patients with a current dsm-iv-tr (diagnostic and statistical manual of mental disorders 4th ed. text rev.) diagnosed with a major depressive episode entered this cross-sectional study. thi...