We present data showing that some foods preserved in lacquer-coated cans and the liquid in them may acquire estrogenic activity. Hormonal activity was measured using the E-screen bioassay. The biological activity of vegetables packed in cans was a result of plastic monomers used in manufacturing the containers. The plastic monomer bisphenol-A, identified by mass spectrometry, was found as a con...

KEYWORD: bisphenol A; immune-affinity column; high-performance liquid chromatography ABSTRACT: A rapid and sensitive method using immuno-affinity columns (IACs) as sample purification procedure and high-performance liquid chromatography (HPLC) tandem fluorescence detector (FLD) for detection has been developed for the determination of bisphenol A (BPA) in beer. The limit of detection (LOD) is 0...

Bisphenol A (BPA) is being removed from many consumer products because of concerns about the chemical’s potential to disrupt the endocrine system. A chemical analog known as bisphenol S (BPS) has been adopted as an alternative in products such as water and baby bottles, thermal paper, and linings of metal cans. In this issue of EHP, a new study shows that BPS has nearly identical impacts on the...

Perturbations in the foetal environment predispose individuals to diseases that become apparent in adulthood. These findings prompted researchers to hypothesize that foetal exposure to environmental oestrogens may play a role in the increased incidence of breast cancer observed in European and US populations over the last 50 years. There is widespread human exposure to bisphenol A, an oestrogen...

BACKGROUND Increasing concern over bisphenol A (BPA) as an endocrine-disrupting chemical and its possible effects on human health have prompted the removal of BPA from consumer products, often labeled "BPA-free." Some of the chemical replacements, however, are also bisphenols and may have similar physiological effects in organisms. Bisphenol S (BPS) and bisphenol F (BPF) are two such BPA substi...

Bisphenol A (BPA) and its substitutes bisphenol S (BPS) F (BPF) are endocrine disrupting chemicals widely used in the production of polycarbonate plastics, epoxy resins thermal papers. The aim review was to identify occupational studies using human biomonitoring (HBM) as a tool for exposure assessment characterize research gaps on topic part HBM4EU project. Hence, systematic literature search P...

Bisphenol A is a widespread industrial chemical which over the past decade has demonstrated its toxicity as an endocrine disruptor. Chlorine present in drinking water may react with bisphenol A to form chlorinated derivatives, which have demonstrated a heightened level of estrogenic activity. In this work, we have comprehensively validated a method using on-line SPE-UPLC-MS/MS and isotope dilut...