نتایج جستجو برای: bsmi polymorphism and vitamin d receptor gene
تعداد نتایج: 17155683 فیلتر نتایج به سال:
Background and purpose: Osteoporosis is a multiple disease that is characterized by decrease in bone mass and bone strength. This decrease is more common in postmenopausal women due to decreased estrogen levels. Vitamin D3 plays a pivotal role in skeletal metabolism by binding to nuclear steroid receptors (receptors for vitamin D (VDR)). This study aimed at investigating the relationship betwee...
BACKGROUND Previous studies have investigated the association between the vitamin D receptor (VDR) BsmI polymorphism and colorectal cancer (CRC) susceptibility, but the results were conflicting. The aim of this study is to quantitatively summarize the relationship between this polymorphism and CRC risk. MATERIALS AND METHODS Two investigators independently searched the Medline, Embase, China ...
Cardiovascular disease due to atherosclerosis is the major determinant of morbidity and mortality in uremic patients. Inflammation is essential in the development of atherosclerosis and markers of inflammation, in particular C-reactive protein, predict the cardiovascular risk. Vitamin D exerts its effects through the Vitamin D Receptor, coded for by a gene showing several polymorphisms associat...
multiple sclerosis (ms) is a multifactorial disease (caused by both environmental and genetic features) that could results from a demyelination of the myelin sheath. subsequently, it leads to many scars or lesions in different places within the central nervous system. the symptoms that occur depend on the site and rigorousness of the lesions and this is why people with ms experience different s...
To explore the relationship between vitamin D receptor gene (ApaI, BsmI) genotypes and allele frequency and mild cognitive impairment in Xinjiang Uygur population. The polymorphisms of the VDR genotypes (ApaI and BsmI) were analyzed by Snapshot method in 124 MCI patients and 124 controls. A allele of ApaI gene increased the risk of MCI [OR = 1.62, 95% CI (1.13-2.31)]; AA genotype increased the ...
PURPOSE Prostate Cancer (PCa) is one of the most common cancers in men and its early detection can provide a high chance of cure. The detection of Vitamin D Receptor (VDR) gene polymorphisms may be useful as a molecular indicator of clinical outcome, once VDR is implicated in a wide variety of biological processes including modulation of the immune response and inhibition of cancer cell growth,...
The vitamin D/Vitamin D receptor (VDR) axis is crucial for human health as it regulates the expression of genes involved in different functions, including calcium homeostasis, energy metabolism, cell growth and differentiation, immune responses. In particular, D/VDR complex both innate adaptive immunity. Autoimmune diseases are believed to arise from a genetic predisposition presence triggers s...
نمودار تعداد نتایج جستجو در هر سال
با کلیک روی نمودار نتایج را به سال انتشار فیلتر کنید