Cytoplasmic Ca(2+) concentration ([Ca(2+)](i)) variation is a key event in myoblast differentiation, but the mechanism by which it occurs is still debated. Here we show that increases of extracellular Ca(2+) concentration ([Ca(2+)](o)) produced membrane hyperpolarization and a concentration-dependent increase of [Ca(2+)](i) due to Ca(2+) influx across the plasma membrane. Responses were not rel...

Sustained high concentration of glucose has been verified toxic to β-cells. Glucose augments Ca(2+)-stimulated insulin release in pancreatic β-cells, but chronic high concentration of glucose could induce a sustained level of Ca(2+) in β-cells, which leads to cell apoptosis. However, the mechanism of high glucose-induced β-cell apoptosis remains unclear. In this study, we use a calcium channel ...

1. Some features of the osmoregulatory mechanism are compared in four populations of Paranephrops zeal andicus White collected form freshwaters of different ionic concentrations. 2. Crayfish from freshwaters of ca, 2-0 mM-NaCl concentration show a sustained decrease in blood concentration of ca. 8% when placed in 0-2 mM-NaCl. 3. Populations from freshwaters of ca. 0-2-0-4 mM-NaCl show lower rat...

It is widely recognized that carbonic anhydrase (CA) participates in silicate weathering and carbonate formation. Nevertheless, it is still not known if the magnitude of the effect produced by CA on surface rock evolution changes or not. In this work, CA gene expression from Bacillus mucilaginosus and the effects of recombination protein on wollastonite dissolution and carbonate formation under...

The extracellular Ca-sensing receptor (CaR) links changes in the concentration of extracellular Ca to changes in cell function. For cells involved in the control of systemic Ca concentration, this provides an efficient receptor-mediated mechanism to rapidly counteract slight fluctuations in the circulating concentration of Ca. However, all cells that express the CaR are not necessarily involved...

The effect of [10]-gingerol on cytosol free Ca(2+) concentration ([Ca(2+)](i)) and viability is large unknown. This study examines the early signaling effects of [10]-gingerol on human colorectal cancer cells. It was found that this compound caused a slow and sustained rise of [Ca(2+)](i) in a concentration-dependent manner. [10]-Gingerol also induced a [Ca(2+)](i) rise when extracellular Ca(2+...

the concentration contents of ca, mg, sr and zn in porites corals from pulau langkawi, pulau redang and pulau tioman were presented. the corals were cleaned and the growth rate examined visually. the growth rate of porites in malaysia waters was between 5 to 25 mm yr-1 and each band was selected for determining the metal contents using the atomic absorption spectrophotometer (aas). the mean val...

Several features, taken together, make Ca 2 1 stand out among the physiologically important cations: first, the concentration of “free” Ca 2 1 ([Ca 2 1 ]) in the cytoplasm is only z 100 nM; second, Ca 2 1 binds with high affinity (dissociation constants from z 100 nM to z 10 m M) to many intracellular proteins that activate/control a wide variety of biochemical/cell physiological events; and th...

Elevation of extracellular Ca(2+) concentration induces intracellular Ca(2+) signaling in parathyroid cells. The response is due to stimulation of the phospholipase C/Ca(2+) pathways, but the direct mechanism responsible for the rise of intracellular Ca(2+) concentration has remained elusive. Here, we describe the electrophysiological property associated with intracellular Ca(2+) signaling in f...