In this present cardioprotective activity study the crude powder of the Hyoscyamus niger Linn is administered to the male albino rats at the dose of 100mg/100g.b.wt. The markers of cardiac function test assess the normal functioning of heart. If there is a change in their normal values of these makers it indicates the dysfunction of heart. Biochemical parameters like TGL, Ck-MB and LPO were car...

Statin drugs have previously been shown to very significantly reduce cardiovascular disease events in a number of large clinical trials.1 As a result, statins are now considered to represent one of the most powerful classes of agents for the treatment of cardiovascular diseases.2 Statins are rapidly becoming frontline therapy for diabetes mellitus, hypertension, and other known cardiovascular d...

Cardiovascular risk reduction has been the target of several large clinical trials in the last decade. As the activation of the renin-angiotensin-aldosterone system (RAAS) plays a central role in the pathogenesis of atherosclerosis and cardiovascular disease, RAAS blockade has been suggested to be among the most efficient cardioprotective interventions, as revealed with the angiotensin converti...

Background: Oxidation of apolipoprotein A-I by myeloperoxidase has been proposed to deprive HDL of its cardioprotective effects. Result: Tyrosine 192 is the major site of chlorination in apoA-I in both plasma and lesion HDL isolated from humans. Conclusion: Chlorination of apolipoprotein A-I by myeloperoxidase generates a dysfunctional form of HDL in vivo. Significance: Quantifying apolipoprote...

Epidemiological studies have suggested an inverse correlation between red wine consumption and the incidence of cardiovascular and neurodegenerative disorders. Although white wines are generally low in polyphenol content as compared to red wines, Champagne wines have been shown to contain relatively high amounts of phenolic acids that may exert protective cellular actions in vivo. In this study...

Withania somnifera Dunal (Ashwangdha), a popular medicinal herb of Ayurveda is used for health, vitality, longevity and rejuvenation properties. It is a common ingredient of polyherbal or herbomineral formulations and used for preventive or therapeutic polypharmaceutical use. Present article emphasized on the studies, which provides the pharmacological basis of its use in cardiovascular disease...

BACKGROUND Adherence to cardioprotective medications in the year after acute coronary syndrome hospitalization is generally poor and is associated with increased risk of rehospitalization and mortality. Few interventions have specifically targeted this high-risk patient population to improve medication adherence. We hypothesize that a multifaceted patient-centered intervention could improve adh...

Cai, Dongqing, Munira Xaymardan, Jacquelyne M. Holm, Jingang Zheng, Jorge R. Kizer, and Jay M. Edelberg. Age-associated impairment in TNFcardioprotection from myocardial infarction. Am J Physiol Heart Circ Physiol 285: H463–H469, 2003. First published May 8, 2003; 10.1152/ajpheart.00144.2003.—Age-associated dysfunction in cardiac microvascular endothelial cells with impaired induction of cardio...

It is estimated that by 2035, more than 130 million adults will suffer from various types of cardiovascular diseases. Therefore, it is very important to know the pathogens of cardiac diseases and investigate new treatments. Also, despite continuous progress in diagnosis, patient education, and risk factor management, myocardial infarction (MI) remains one of the most common causes of morbidity,...

BACKGROUND Although several studies have assessed the price of different food groups in developed countries, there is scarce evidence regarding developing countries. Also, there is no report regarding the price of cardioprotective compared with unhealthy foods. The aim of this study was to determine the trend of food cost across different food groups (cardioprotective vs. unhealthy) and to asse...