The present study aimed to identify the differentially expressed genes (DEGs) between lung adenocarcinoma and normal lung tissues, and between lung squamous cell carcinoma and normal lung tissues, with the purpose of identifying potential biomarkers for the treatment of lung cancer. The gene expression profile (GSE6044) was downloaded from the Gene Expression Omnibus database, which included da...

Renal cell carcinoma (RCC) usually metastasizes to lung, liver, bone and brain. We report a case of an elderly man who underwent radical nephrectomy for renal developed metastasis in the plane between contralateral psoas muscle quadratus lumborum 11 years after operation J Enam Med Col 2021; 11(1): 52-54

cisplatin-based chemotherapy is the standard treatment for advanced non-small cell lung cancer (nsclc). many novel drugs have been used in combination with cisplatin in this setting. of these drugs, gemcitabine is reported to have a high response rate and acceptable toxicity. the aim of this study was to evaluate the efficacy and safety of gemcitabine and cisplatin combination. twentythree pati...

giant cell carcinoma of the endometrium is a rare and an aggressive tumor that should be distinguished from other endometrial tumors with a prominent giant cell component, including trophoblastic tumors, certain primary sarcomas, and malignant mixed müllerian tumors. at present, cumulative data on this rare histological variant is limited and the prognostic significance of the presence and the ...

aims: the backbone of treatment in advanced non-small cell lung cancer is platinum-based doublet chemotherapy. we intended to compare the effectiveness of two commonly used regimens in real world practice. methods: this single institute, parallel comparative post marketing study included 100 patients with chemo-naïve advanced (stage iiib, iv) non-small cell lung cancer and eastern cooperative o...

TOPIC: Lung Cancer TYPE: Medical Student/Resident Case Reports INTRODUCTION: Large-cell neuroendocrine carcinoma (LCNEC) is a rare form of pulmonary tumors with features small cell lung and non-small cancer. Due to its rarity, there little known about presentation prognosis. We review 2 cases LCNEC different outcomes which will help contribute the current literature LCNEC. CASE PRESENTATION: Pa...

Since the preliminary analyses of the glycolipids of small cell carcinomas of the lung showed an increase of GM2 ganglioside, we generated new murine monoclonal antibodies directed to GM2 to identify the molecular species of the glycolipid. The monoclonal antibodies MK2-34 and MK1-16 (both IgM), which specifically detect N-glycolyl GM2 and N-acetyl GM2, respectively, were generated by immunizin...

the aim of this study is to determine whether there is a role of podoplanin and glutathione s-transferases t1 (gst-t1) expression in laryngeal squamous cell carcinoma. the study was completed with 33 patients and gene expression analysis was performed by qrt–pcr. the podoplanin and gst-t1 expression patterns were analyzed to determine their correlation with clinicopathologic parameters of laryn...

Background Lung cancer is one of the leading cause related death. Most common histopathology lung non-small cell carcinoma which adenocarcinoma most common. There are limited number studies done in Nepal to know different aspects cancer.
 Objective To demographic parameters patients diagnosed as a university hospital. The study also aims histopathological diagnosis Method All presenting ou...

BACKGROUND To make the difference between two uncommon entities, small cell prostate carcinoma and prostatic metastasis of small cell lung cancer. METHODS We describe a case of single extrapulmonar metastasis in the prostate from small lung carcinoma. RESULTS We describe a case of single extrapulmonar metastasis in the prostate from small lung carcinoma. CONCLUSIONS Clinical and radiograp...