biomolecular behavior of tumor cells has become attractive to investigators. p53 as an oncosuppresor gene has been core of various studies and ki67 is a nuclear protein involved in proliferation process. stopping of onco-suppressor function theoretically allows proliferative system to get out of any control. in this case-control study we evaluated 50 patients with non small cell lung cancer, co...

background: lung cancer ranks among the most common and most lethal malignancies worldwide. once vascular or lymphatic invasions occur, metastatic dissemination to distant sites is common. bone, liver, adrenals, and brain are the most frequent sites of the distant disease. in this study we present a case of squamous cell carcinoma of lung with metastasis of the left knee bursa.case presentation...

background: the aberrant expression of dickkopf-1 (dkk1), triose phosphate isomerase (tpi) and fatty acid binding-protein 5 (fabp5) in lung cancer tissues and their presence in secretome of lung cancer cell lines were reported. here, serum levels of these molecules in lung cancer patients were compared to those in a healthy control group. materials and methods: the patients’ group consisted of ...

conclusion the technical performance of pet scan is significantly higher than similar technologies for staging and treatment of nsclc. in addition, it might slightly improve the treatment process and lead to a small level of increase in the quality adjusted life year (qaly) gained by these patients making it cost-effective for the treatment of nsclc. results the total annual running cost of a p...

Miliary mottling on chest radiography is seen in miliary tuberculosis, certain fungal infections, sarcoidosis, coal miner’s pneumoconiosis, silicosis, hemosiderosis, fibrosing alveolitis, acute extrinsic allergic alveolitis, pulmonary eosinophilic syndrome, pulmonary alveolar proteinosis, and rarely in hematogenous metastases from the primary cancers of the thyroid, kidney, trophoblasts, and so...

miliary mottling on chest radiography is seen in miliary tuberculosis, certain fungal infections, sarcoidosis, coal miner’s pneumoconiosis, silicosis, hemosiderosis, fibrosing alveolitis, acute extrinsic allergic alveolitis, pulmonary eosinophilic syndrome, pulmonary alveolar proteinosis, and rarely in hematogenous metastases from the primary cancers of the thyroid, kidney, trophoblasts, and so...

Background: Lung cancer ranks among the most common and most lethal malignancies worldwide. Once vascular or lymphatic invasions occur, metastatic dissemination to distant sites is common. Bone, liver, adrenals, and brain are the most frequent sites of the distant disease. In this study we present a case of squamous cell carcinoma of lung with metastasis of the left knee bursa.Case presentation...

Background & objective: The histologic distinction of small cell from non-small cell lung carcinoma and correct identification of all subtypes of lung carcinoma are very important in treatment management. The main method for histologic classification of lung tumors is based on morphology. However, in small bronchoscopic biopsies in par...