نتایج جستجو برای: chelating agent
تعداد نتایج: 263141 فیلتر نتایج به سال:
Cell invasion and angiogenesis are crucial processes in cancer metastasis that require extracellular matrix (ECM) degradation. Proteolytic degradation of the ECM components is a central event of invasion and angiogenesis processes. During these processes, matrix metalloproteinases (MMPs) seem to be primarily responsible for much of the ECM degradation. Disulfiram is frequently used in the treat...
Aims: Several chelating agents are presently used among environmental physicians to diagnose and treat a chronic metal overexposure. We evaluated and compared the binding capacity of the most common chelating agents DMPS (2, 3-dimercapto-1propanesulfonic acid), DMSA (dimercaptosuccinic acid), also called Succimer) and EDTA (ethylene diamine tetraacetic acid) for the potentially toxic metals Ant...
Dispersive liquid–liquid microextraction (DLLME) combined with inductively coupled plasma-atomic emission spectrometry (ICP-AES) was applied for the determination of lead in different environmental water samples. Ammonium pyrrolidine dithiocarbamate (APDC), chloroform and ethanol were used as chelating agent, extraction solvent and disperser solvent, respectively. The effective parameters, such...
Background and purpose: Patients with Beta thalassemia major need consistent blood transfusion from early years of life. Deferasirox is used as an oral chelating agent (once daily) to excrete excess iron. This study aimed to compare the efficacy of deferasirox twice daily and the usual once daily dosing. Materials and methods: This before after clinical trial was performed in 2013-2014 in pati...
Highly homogeneous transparent titania gels have been successfully prepared from titanium alkoxide by a sol–gel method utilizing chelating agent, ethyl acetylacetate (EtAcAc), in the presence of strong acid anions. Only catalytic amount of a strong acid anion suppress the rapid hydrolysis of titanium alkoxide by blocking the nucleophilic attack of HO and H2O, and the resultant moderate sol–gel ...
The performance of modified Fenton (MF) treatment to promote PAH oxidation in artificially contaminated soil was investigated in packed soil column with a hydrogen peroxide (H2O2) delivery system simulating in situ injection. Soil samples were spiked with phenanthrene (low molecular weight PAH) and fluoranthene (high molecular weight PAH) to an initial concentration of 500 mg/kg dried soil each...
Transfusion-associated iron overload induces systemic toxicity. Deferasirox, a convenient long acting oral agent, has recently been introduced in clinical practice with a promising efficacy. But there are some patients who experience drug-related toxicities and cannot tolerate it. To investigate effect of genetic variations on the toxicities and find optimal target population, we analyzed the g...
Glyphosate-based herbicides (GBHs), consisting of glyphosate and formulants, are the most frequently applied herbicides worldwide. The declared active ingredient glyphosate does not only inhibit the EPSPS but is also a chelating agent that binds macro- and micronutrients, essential for many plant processes and pathogen resistance. GBH treatment may thus impede uptake and availability of macro- ...
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