Approximately 75% of adults over the age of 65 years are affected by two or more chronic medical conditions. We provide a conceptual justification for individualized absolute risk calculators for competing patient-centered outcomes (PCO) (i.e. outcomes deemed important by patients) and patient reported outcomes (PRO) (i.e. outcomes patients report instead of physiologic test results). The absol...

Failure to recognize the presence of competing risk or to account for it may result in misleading conclusions. We aimed to perform a competing risk analysis to assess the efficacy of the low molecular weight heparin dalteparin versus unfractionated heparin (UFH) in venous thromboembolism (VTE) in medical-surgical critically ill patients, taking death as a competing risk.This was a secondary ana...

recent years have witnessed a parallel and seemingly contradictory trend towards both the standardization and the customization of healthcare and medical treatment. here, we explore what is meant by ‘standardization’ and ‘customization’ in healthcare settings and explore the implications of these changes for healthcare delivery. we frame the paradox of these divergent and opposing factors in te...

BACKGROUND Modelling competing risks is an essential issue in Nephrology Research. In peritoneal dialysis studies, sometimes inappropriate methods (i.e. Kaplan-Meier method) have been used to estimate probabilities for an event of interest in the presence of competing risks. In this situation a competing risk analysis should be preferable. The objectives of this study are to describe the bias r...

Much operational reliability data available, e.g., in the nuclear industry, is heavily right-censored by preventive maintenance. The common methods for dealing with right-censored data (Total Time on Test statistic, Kaplan–Meier estimator, adjusted rank methods) assume the -independent competing-risk model for the underlying failure process and the censoring process, even though there are many ...

Background: Survival analysis is a collection of statistical methods for inference on time-to-event data. If several causes of failure occur and the occurrence of one event precludes the occurrence of the other events, the situation is known as competing risks. Since the competing risks violate the fundamental assumption of independent censoring, specific methods for inference are needed. Objec...

To investigate the recently described Lee mortality index as predictor of mortality after radical cystectomy. A total of 735 patients who underwent radical cystectomy for bladder cancer between 1993 and 2010 were studied. Median patient age was 67 years and the median follow-up was 7.8 years (censored patients). The Lee mortality index was assigned based on data derived from patient history, pr...

aim : this study aims to investigate some clinical and pathologic factors associated with the prognosis of patients with colon and rectum cancers separately. background : colorectal cancer is the most common cancer of the digestive system and also the fourth cause of cancer-related deaths around the world. different studies indicate that survival of patients with colorectal cancer has improved ...