Introduction: Infants born with congenital anomalies demand individualized nutritional evaluations and recommendations. The anatomical changes of neonatal surgical diseases create specific physiological constraints.Patients with different congenital anomalies have different nutritional support needs. It is essential to know the exact physiology of these anomalies in order to be able to manage a...

Holt-Oram syndrome is an autosomal dominant disorder, characterised by skeletal abnormalities of the upper limb associated with congenital heart defect, mainly atrial and ventricular septal defects. Skeletal defects exclusively affect the upper limbs in the preaxial radial ray distribution and are bilateral and asymmetrical. They range from clinodactyly, absent or digitalised thumb, hypoplastic...

Congenital heart diseases are traditionally considered to be multifactorial in pathogenesis resulting from environmental and genetic interactions that determine penetrance and expressivity within a genetically predisposed family. Recent evidence suggests that genetic contributions have been significantly underestimated. However, single gene defects occur only in a minority of cases, and multige...

BACKGROUND AND PURPOSE PHACES syndrome is a neurocutaneous disorder of unknown etiology. We studied the spectrum of associated congenital and progressive cerebral vascular anomalies. METHODS The medical records of 7 patients with PHACES syndrome were reviewed and combined with an additional 108 PHACES cases identified from the literature. We reviewed the clinical characteristics, calculated t...

Coronary artery fistula (CAF) is an abnormal communication between an epicardial coronary artery and a single or multiple cardiac chambers, large vessels or other vascular structures (1). Although it is a rare condition, it is the most frequent congenital coronary anomaly (2), and it accounts for 0.2-0.4% of congenital cardiac anomalies. Approximately 50% of pediatric coronary vasculature anoma...

BACKGROUND Increased risk of various congenital anomalies has been reported to be associated with trihalomethane (THM) exposure in the water supply. OBJECTIVES We conducted a registry-based study to determine the relationship between THM concentrations and the risk of congenital anomalies in England and Wales. METHODS We obtained congenital anomaly data from the National Congenital Anomalie...

OBJECTIVE To identify the proportion of major structural noncardiac anomalies identified with congenital heart defects (CHDs). STUDY DESIGN Records of infants with CHDs in the Metropolitan Atlanta Congenital Defects Program who were born during the period 1968 through 2005 were classified as having isolated, syndromic, multiple CHD (ie, having an unrecognized pattern of multiple congenital an...

background: the most common congenital abnormality of esophagus is esophageal atresia (ea) that can occur with or without tracheoesophageal fistula. other associated anomalies are the leading cause of death in these patients. the present study aimed to evaluate the main complication, outcomes and cause of death in neonate with ea repaired in amirkola children’s hospital (ach), iran within a 13 ...